Description
Product Name: | Cyclin B2 Rabbit mAb |
Product Code: | CAB7956 |
Size: | 20uL, 50uL, 100uL |
Synonyms: | HsT17299 |
Applications: | WB, IHC, IF |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | A synthesized peptide derived from human Cyclin B2 |
Applications: | WB, IHC, IF |
Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | Rat testis |
Immunogen: | A synthesized peptide derived from human Cyclin B2 |
Purification Method: | Affinity purification |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 9133 |
Uniprot: | O95067 |
Calculated MW: | 45kDa |
Observed MW: | 45KDa |
UniProt Protein Function: | CCNB2: Essential for the control of the cell cycle at the G2/M (mitosis) transition. Belongs to the cyclin family. Cyclin AB subfamily. |
UniProt Protein Details: | Protein type:Cell cycle regulation Chromosomal Location of Human Ortholog: 15q22.2 Cellular Component: microtubule cytoskeleton; nucleoplasm; centrosome; membrane; cytosol Molecular Function:protein binding; protein kinase binding Biological Process: mitosis; thymus development; cell division; regulation of cell cycle; in utero embryonic development; mitotic nuclear envelope disassembly; T cell homeostasis; regulation of cyclin-dependent protein kinase activity; mitotic cell cycle; G2/M transition of mitotic cell cycle; growth |
NCBI Summary: | Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control. [provided by RefSeq, Jul 2008] |
UniProt Code: | O95067 |
NCBI GenInfo Identifier: | 5921731 |
NCBI Gene ID: | 9133 |
NCBI Accession: | O95067.1 |
UniProt Related Accession: | O95067 |
Molecular Weight: | ~ 45kDa |
NCBI Full Name: | G2/mitotic-specific cyclin-B2 |
NCBI Synonym Full Names: | cyclin B2 |
NCBI Official Symbol: | CCNB2 |
NCBI Official Synonym Symbols: | HsT17299 |
NCBI Protein Information: | G2/mitotic-specific cyclin-B2 |
UniProt Protein Name: | G2/mitotic-specific cyclin-B2 |
Protein Family: | Light-harvesting protein |
UniProt Gene Name: | CCNB2 |
UniProt Entry Name: | CCNB2_HUMAN |