Anti-Cyclin A1/A2 Antibody (CAB2635)
- SKU:
- CAB2635
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Description
| Product Name: | Cyclin A1/A2 Rabbit mAb |
| Product Code: | CAB2635 |
| Size: | 20uL, 50uL, 100uL |
| Applications: | WB, IP |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Cyclin A1/A2. |
| Applications: | WB, IP |
| Recommended Dilutions: | WB 1:500 - 1:2000 IP 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HCT116, Jurkat, Mouse thymus |
| Immunogen: | A synthesized peptide derived from human Cyclin A1/A2. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 890/8900 |
| Uniprot: | P20248/P78396 |
| Calculated MW: | 52, 49kDa |
| Observed MW: | 52KDa/55KDa |
| UniProt Protein Function: | CCNA2: a member of the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions. |
| UniProt Protein Details: | Protein type:Cell cycle regulation; Nuclear receptor co-regulator Chromosomal Location of Human Ortholog: 4q27 Cellular Component: nucleoplasm; male pronucleus; cytoplasm; female pronucleus; nucleus Molecular Function:protein binding; protein kinase binding Biological Process: mitosis; positive regulation of fibroblast proliferation; organ regeneration; response to glucagon stimulus; cell division; positive regulation of transcription, DNA-dependent; mitotic cell cycle G2/M transition DNA damage checkpoint; regulation of G2/M transition of mitotic cell cycle; Ras protein signal transduction; regulation of cyclin-dependent protein kinase activity; mitotic cell cycle; G2/M transition of mitotic cell cycle; response to estradiol stimulus |
| NCBI Summary: | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members function as regulators of the cell cycle. This protein binds and activates cyclin-dependent kinase 2 and thus promotes transition through G1/S and G2/M. [provided by RefSeq, Aug 2016] |
| UniProt Code: | P20248 |
| NCBI GenInfo Identifier: | 311033358 |
| NCBI Gene ID: | 890 |
| NCBI Accession: | P20248.2 |
| UniProt Related Accession: | P20248 |
| Molecular Weight: | ~ 49kDa |
| NCBI Full Name: | Cyclin-A2 |
| NCBI Synonym Full Names: | cyclin A2 |
| NCBI Official Symbol: | CCNA2 |
| NCBI Official Synonym Symbols: | CCN1; CCNA |
| NCBI Protein Information: | cyclin-A2 |
| UniProt Protein Name: | Cyclin-A2 |
| Protein Family: | Protein |
| UniProt Gene Name: | CCNA2 |
| UniProt Entry Name: | CCNA2_HUMAN |
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