Immunology Antibodies 3
Anti-CXCR5 Antibody (CAB8950)
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- SKU:
- CAB8950
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Immunology
Description
| Antibody Name: | Anti-CXCR5 Antibody |
| Antibody SKU: | CAB8950 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human CXCR5 |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Jurkat, K-562, Mouse lung, Mouse spleen, Mouse thymus, Rat thymus |
| Immunogen: | A synthesized peptide derived from human CXCR5 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 643 |
| Uniprot: | P32302 |
| Cellular Location: | |
| Calculated MW: | 42kDa |
| Observed MW: | 45KDa |
| Synonyms: | BLR1, CD185, MDR15 |
| Background: | This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011] |
| UniProt Protein Function: | CXCR5: Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 11q23.3 Cellular Component: integral to plasma membrane; plasma membrane; external side of plasma membrane Molecular Function:G-protein coupled receptor activity; protein binding; C-X-C chemokine receptor activity Biological Process: positive regulation of cytokinesis; G-protein coupled receptor protein signaling pathway; B cell activation; immune response; cell motility; chemotaxis; lymph node development |
| NCBI Summary: | This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011] |
| UniProt Code: | P32302 |
| NCBI GenInfo Identifier: | 416718 |
| NCBI Gene ID: | 643 |
| NCBI Accession: | P32302.1 |
| UniProt Related Accession: | P32302 |
| Molecular Weight: | |
| NCBI Full Name: | C-X-C chemokine receptor type 5 |
| NCBI Synonym Full Names: | C-X-C motif chemokine receptor 5 |
| NCBI Official Symbol: | CXCR5 |
| NCBI Official Synonym Symbols: | BLR1; CD185; MDR15 |
| NCBI Protein Information: | C-X-C chemokine receptor type 5 |
| UniProt Protein Name: | C-X-C chemokine receptor type 5 |
| UniProt Synonym Protein Names: | Burkitt lymphoma receptor 1; Monocyte-derived receptor 15; MDR-15; CD_antigen: CD185 |
| UniProt Gene Name: | CXCR5 |
| UniProt Entry Name: | CXCR5_HUMAN |
 | Western blot - CXCR5 Rabbit mAb (CAB8950) |
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