Immunology Antibodies 2

Anti-CXCL9 Antibody (CAB1864)

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SKU:
CAB1864
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology

Description

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Antibody Name:Anti-CXCL9 Antibody
Antibody SKU:CAB1864
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human CXCL9 (NP_002407.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:THP-1, A-431, 293T
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human CXCL9 (NP_002407.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:KQFA PSPS CEKI EIIA TLKN GVQT CLNP DSAD VKEL IKKW EKQV SQKK KQKN GKKH QKKK VLKV RKSQ RSRQ KKTT
Gene ID:4283
Uniprot:Q07325
Cellular Location:Secreted
Calculated MW:14kDa
Observed MW:14kDa
Synonyms:CXCL9, CMK, Humig, MIG, SCYB9, crg-10
Background:This antimicrobial gene encodes a protein thought to be involved in T cell trafficking. The encoded protein binds to C-X-C motif chemokine 3 and is a chemoattractant for lymphocytes but not for neutrophils.
UniProt Protein Function:CXCL9: Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3. Belongs to the intercrine alpha (chemokine CxC) family.
UniProt Protein Details:

Protein type:Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 4q21

Cellular Component: extracellular space; extracellular region; external side of plasma membrane

Molecular Function:protein binding; CXCR3 chemokine receptor binding; chemokine activity; cytokine activity

Biological Process: positive regulation of leukocyte chemotaxis; response to lipopolysaccharide; defense response; positive regulation of cAMP metabolic process; signal transduction; chemotaxis; positive regulation of myoblast differentiation; regulation of cell proliferation; G-protein coupled receptor protein signaling pathway; cell-cell signaling; cellular defense response; immune response; positive regulation of release of sequestered calcium ion into cytosol; inflammatory response; defense response to virus

NCBI Summary:This antimicrobial gene encodes a protein thought to be involved in T cell trafficking. The encoded protein binds to C-X-C motif chemokine 3 and is a chemoattractant for lymphocytes but not for neutrophils. [provided by RefSeq, Sep 2014]
UniProt Code:Q07325
NCBI GenInfo Identifier:585487
NCBI Gene ID:4283
NCBI Accession:Q07325.1
UniProt Secondary Accession:Q07325,Q503B4,
UniProt Related Accession:Q07325
Molecular Weight:Approximately 150 kDa
NCBI Full Name:C-X-C motif chemokine 9
NCBI Synonym Full Names:chemokine (C-X-C motif) ligand 9
NCBI Official Symbol:CXCL9  
NCBI Official Synonym Symbols:CMK; MIG; Humig; SCYB9; crg-10  
NCBI Protein Information:C-X-C motif chemokine 9; small-inducible cytokine B9; gamma-interferon-induced monokine; monokine induced by gamma interferon; monokine induced by interferon-gamma
UniProt Protein Name:C-X-C motif chemokine 9
UniProt Synonym Protein Names:Gamma-interferon-induced monokine; Monokine induced by interferon-gamma; HuMIG; MIG; Small-inducible cytokine B9
Protein Family:Migration and invasion enhancer
UniProt Gene Name:CXCL9  
UniProt Entry Name:CXCL9_HUMAN
Anti-CXCL9 Antibody (CAB1864)Western blot analysis of extracts of various cell lines, using CXCL9 antibody (CAB1864) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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