Cell Biology Antibodies 15

Anti-CXCL5 Antibody (CAB2020)

(No reviews yet) Write a Review
SKU:
CAB2020

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-CXCL5 Antibody
Antibody SKU:CAB2020
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 37-114 of human CXCL5 (NP_002985.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 37-114 of human CXCL5 (NP_002985.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:AGPA AAVL RELR CVCL QTTQ GVHP KMIS NLQV FAIG PQCS KVEV VASL KNGK EICL DPEA PFLK KVIQ KILD GGNK EN
Gene ID:6374
Uniprot:P42830
Cellular Location:Secreted
Calculated MW:11kDa
Observed MW:Refer to Figures
Synonyms:CXCL5, ENA-78, SCYB5
Background:This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion.
UniProt Protein Function:CXCL5: Involved in neutrophil activation. In vitro, ENA-78(8- 78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes. Belongs to the intercrine alpha (chemokine CxC) family.
UniProt Protein Details:

Protein type:Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: extracellular space; extracellular region

Molecular Function:chemokine activity; CXCR chemokine receptor binding

Biological Process: G-protein coupled receptor protein signaling pathway; cell-cell signaling; positive regulation of cell proliferation; neutrophil mediated immunity; immune response; positive regulation of leukocyte chemotaxis; response to lipopolysaccharide; chemotaxis; inflammatory response; signal transduction

NCBI Summary:This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion. [provided by RefSeq, May 2013]
UniProt Code:P42830
NCBI GenInfo Identifier:1169525
NCBI Gene ID:6374
NCBI Accession:P42830.1
UniProt Secondary Accession:P42830,Q96QE1,
UniProt Related Accession:P42830
Molecular Weight:11,972 Da
NCBI Full Name:C-X-C motif chemokine 5
NCBI Synonym Full Names:chemokine (C-X-C motif) ligand 5
NCBI Official Symbol:CXCL5  
NCBI Official Synonym Symbols:SCYB5; ENA-78  
NCBI Protein Information:C-X-C motif chemokine 5; neutrophil-activating protein 78; neutrophil-activating peptide ENA-78; epithelial-derived neutrophil-activating protein 78; small inducible cytokine subfamily B (Cys-X-Cys), member 5 (epithelial-derived neutrophil-activating peptide 78)
UniProt Protein Name:C-X-C motif chemokine 5
UniProt Synonym Protein Names:ENA-78(1-78); Epithelial-derived neutrophil-activating protein 78; Neutrophil-activating peptide ENA-78; Small-inducible cytokine B5Cleaved into the following 2 chains:ENA-78(8-78); ENA-78(9-78)
Protein Family:C-X-C motif chemokine
UniProt Gene Name:CXCL5  
UniProt Entry Name:CXCL5_HUMAN
View AllClose

Additional Information

Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
View AllClose

Related Products