Cell Biology Antibodies 15
Anti-CXCL5 Antibody (CAB2020)
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- SKU:
- CAB2020
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CXCL5 Antibody |
| Antibody SKU: | CAB2020 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 37-114 of human CXCL5 (NP_002985.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 37-114 of human CXCL5 (NP_002985.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | AGPA AAVL RELR CVCL QTTQ GVHP KMIS NLQV FAIG PQCS KVEV VASL KNGK EICL DPEA PFLK KVIQ KILD GGNK EN |
| Gene ID: | 6374 |
| Uniprot: | P42830 |
| Cellular Location: | Secreted |
| Calculated MW: | 11kDa |
| Observed MW: | Refer to Figures |
| Synonyms: | CXCL5, ENA-78, SCYB5 |
| Background: | This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion. |
| UniProt Protein Function: | CXCL5: Involved in neutrophil activation. In vitro, ENA-78(8- 78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes. Belongs to the intercrine alpha (chemokine CxC) family. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 4q13.3 Cellular Component: extracellular space; extracellular region Molecular Function:chemokine activity; CXCR chemokine receptor binding Biological Process: G-protein coupled receptor protein signaling pathway; cell-cell signaling; positive regulation of cell proliferation; neutrophil mediated immunity; immune response; positive regulation of leukocyte chemotaxis; response to lipopolysaccharide; chemotaxis; inflammatory response; signal transduction |
| NCBI Summary: | This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion. [provided by RefSeq, May 2013] |
| UniProt Code: | P42830 |
| NCBI GenInfo Identifier: | 1169525 |
| NCBI Gene ID: | 6374 |
| NCBI Accession: | P42830.1 |
| UniProt Secondary Accession: | P42830,Q96QE1, |
| UniProt Related Accession: | P42830 |
| Molecular Weight: | 11,972 Da |
| NCBI Full Name: | C-X-C motif chemokine 5 |
| NCBI Synonym Full Names: | chemokine (C-X-C motif) ligand 5 |
| NCBI Official Symbol: | CXCL5 |
| NCBI Official Synonym Symbols: | SCYB5; ENA-78 |
| NCBI Protein Information: | C-X-C motif chemokine 5; neutrophil-activating protein 78; neutrophil-activating peptide ENA-78; epithelial-derived neutrophil-activating protein 78; small inducible cytokine subfamily B (Cys-X-Cys), member 5 (epithelial-derived neutrophil-activating peptide 78) |
| UniProt Protein Name: | C-X-C motif chemokine 5 |
| UniProt Synonym Protein Names: | ENA-78(1-78); Epithelial-derived neutrophil-activating protein 78; Neutrophil-activating peptide ENA-78; Small-inducible cytokine B5Cleaved into the following 2 chains:ENA-78(8-78); ENA-78(9-78) |
| Protein Family: | C-X-C motif chemokine |
| UniProt Gene Name: | CXCL5 |
| UniProt Entry Name: | CXCL5_HUMAN |
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