Anti-CXCL3 Antibody (CAB14226)
- SKU:
- CAB14226
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CXCL3
- Synonyms:
- CINC-2b
- Synonyms:
- GRO3
- Synonyms:
- GROg
- Synonyms:
- MIP-2b
- Synonyms:
- MIP2B
- Synonyms:
- SCYB3
Description
| Product Name: | CXCL3 Rabbit pAb |
| Product Code: | CAB14226 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | CXCL3, CINC-2b, GRO3, GROg, MIP-2b, MIP2B, SCYB3 |
| Applications: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-107 of human CXCL3 (NP_002081.2). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-107 of human CXCL3 (NP_002081.2). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAHA TLSA APSN PRLL RVAL LLLL LVAA SRRA AGAS VVTE LRCQ CLQT LQGI HLKN IQSV NVRS PGPH CAQT EVIA TLKN GKKA CLNP ASPM VQKI IEKI LNKG STN |
| Gene ID: | 2921 |
| Uniprot: | P19876 |
| Cellular Location: | Secreted |
| Calculated MW: | 11kDa |
| Observed MW: | Refer to Figures |
| UniProt Protein Function: | CXCL3: Ligand for CXCR2. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes. Belongs to the intercrine alpha (chemokine CxC) family. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 4q21 Cellular Component: extracellular space; extracellular region Molecular Function:chemokine activity; CXCR chemokine receptor binding Biological Process: G-protein coupled receptor protein signaling pathway; neutrophil chemotaxis; response to lipopolysaccharide; positive regulation of leukocyte chemotaxis; immune response; inflammatory response; regulation of cell proliferation |
| NCBI Summary: | This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. [provided by RefSeq, Sep 2014] |
| UniProt Code: | P19876 |
| NCBI GenInfo Identifier: | 127086 |
| NCBI Gene ID: | 2921 |
| NCBI Accession: | P19876.1 |
| UniProt Secondary Accession: | P19876,Q4W5H9, |
| UniProt Related Accession: | P19876 |
| Molecular Weight: | 11,342 Da |
| NCBI Full Name: | C-X-C motif chemokine 3 |
| NCBI Synonym Full Names: | chemokine (C-X-C motif) ligand 3 |
| NCBI Official Symbol: | CXCL3 |
| NCBI Official Synonym Symbols: | GRO3; GROg; MIP2B; SCYB3; MIP-2b; CINC-2b |
| NCBI Protein Information: | C-X-C motif chemokine 3; GRO-gamma; MIP2-beta; MGSA gamma; GRO3 oncogene; GRO-gamma(1-73); growth-regulated protein gamma; macrophage inflammatory protein 2-beta; melanoma growth stimulatory activity gamma |
| UniProt Protein Name: | C-X-C motif chemokine 3 |
| UniProt Synonym Protein Names: | GRO-gamma(1-73); Growth-regulated protein gamma; GRO-gamma; Macrophage inflammatory protein 2-beta; MIP2-beta |
| UniProt Gene Name: | CXCL3 |
| UniProt Entry Name: | CXCL3_HUMAN |
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