Cell Biology Antibodies 3

Anti-CXCL2 Antibody (CAB12639)

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SKU:
CAB12639
Product Type:
Antibody
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-CXCL2 Antibody
Antibody SKU:CAB12639
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-107 of human CXCL2 (NP_002080.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Rat
Positive Samples:Rat lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-107 of human CXCL2 (NP_002080.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MARA TLSA APSN PRLL RVAL LLLL LVAA SRRA AGAP LATE LRCQ CLQT LQGI HLKN IQSV KVKS PGPH CAQT EVIA TLKN GQKA CLNP ASPM VKKI IEKM LKNG KSN
Gene ID:2920
Uniprot:P19875
Cellular Location:Secreted
Calculated MW:11kDa
Observed MW:11kDa
Synonyms:CXCL2, CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, MIP2, MIP2A, SCYB2
Background:This antimicrobial gene is part of a chemokine superfamily that encodes secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CXC subfamily, is expressed at sites of inflammation and may suppress hematopoietic progenitor cell proliferation.
UniProt Protein Function:Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.
NCBI Summary:This antimicrobial gene is part of a chemokine superfamily that encodes secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CXC subfamily, is expressed at sites of inflammation and may suppress hematopoietic progenitor cell proliferation. [provided by RefSeq, Sep 2014]
UniProt Code:P19875
NCBI GenInfo Identifier:127085
NCBI Gene ID:2920
NCBI Accession:P19875.1
UniProt Secondary Accession:P19875,Q6FGD6, Q9UPB8,
UniProt Related Accession:P19875
Molecular Weight:11,389 Da
NCBI Full Name:C-X-C motif chemokine 2
NCBI Synonym Full Names:C-X-C motif chemokine ligand 2
NCBI Official Symbol:CXCL2  
NCBI Official Synonym Symbols:GRO2; GROb; MIP2; MIP2A; SCYB2; MGSA-b; MIP-2a; CINC-2a  
NCBI Protein Information:C-X-C motif chemokine 2
UniProt Protein Name:C-X-C motif chemokine 2
UniProt Synonym Protein Names:Growth-regulated protein beta; Gro-beta
Protein Family:C-X-C motif chemokine
UniProt Gene Name:CXCL2  
UniProt Entry Name:CXCL2_HUMAN
Anti-CXCL2 Antibody (CAB12639)Western blot analysis of extracts of rat lung, using CXCL2 antibody (CAB12639) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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