Epigenetics & Nuclear Signaling Antibodies 1

Anti-CWC22 Antibody (CAB13116)

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SKU:
CAB13116
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-CWC22 Antibody
Antibody SKU:CAB13116
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 639-908 of human CWC22 (NP_065994.1).
Application:WB
Recommended Dilution:WB 1:1000 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse liver, Mouse testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 639-908 of human CWC22 (NP_065994.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:LTDE LREH LKNT PKVI VAQK PDVE QNKS SPSS SSSA SSSS ESDS SDSD SDSS DSSS ESSS EESD SSSI SSHS SASA NDVR KKGH GKTR SKEV DKLI RNQQ TNDR KQKE RRQE HGHQ ETRT ERER RSEK HRDQ NSSG SNWR DPIT KYTS DKDV PSER NNYS RVAN DRDQ EMHI DLEN KHGD PKKK RGER RNSF SENE KHTH RIKD SENF RRKD RSKS KEMN RKHS GSRS DEDR YQNG AERR WEKS SRYS EQSR ESKK NQDR RREK SPAK QK
Gene ID:57703
Uniprot:Q9HCG8
Cellular Location:Nucleus, Nucleus speckle
Calculated MW:105kDa
Observed MW:110kDa
Synonyms:CWC22, EIF4GL, NCM, fSAPb
Background:
UniProt Protein Function:NCM: a component of the spliceosome C complex.
UniProt Protein Details:

Protein type:RNA processing; RNA splicing; Spliceosome

Chromosomal Location of Human Ortholog: 2q31.3

Cellular Component: cytoplasm; Golgi apparatus; nuclear speck; nucleoplasm; spliceosome

Molecular Function:protein binding; RNA binding

Biological Process: nuclear mRNA splicing, via spliceosome; regulation of nuclear mRNA splicing, via spliceosome

UniProt Code:Q9HCG8
NCBI GenInfo Identifier:296439380
NCBI Gene ID:57703
NCBI Accession:Q9HCG8.3
UniProt Secondary Accession:Q9HCG8,Q05DC2, Q4G135, Q52LF0, Q6PEX2, Q7Z6I0, Q9H5L3 Q9H6Q6,
UniProt Related Accession:Q9HCG8
Molecular Weight:105,466 Da
NCBI Full Name:Pre-mRNA-splicing factor CWC22 homolog
NCBI Synonym Full Names:CWC22 homolog, spliceosome-associated protein
NCBI Official Symbol:CWC22  
NCBI Official Synonym Symbols:NCM; fSAPb; EIF4GL  
NCBI Protein Information:pre-mRNA-splicing factor CWC22 homolog
UniProt Protein Name:Pre-mRNA-splicing factor CWC22 homolog
UniProt Synonym Protein Names:Nucampholin homolog; fSAPb
Protein Family:Pre-mRNA-splicing factor
UniProt Gene Name:CWC22  
UniProt Entry Name:CWC22_HUMAN
Anti-CWC22 Antibody (CAB13116)Western blot analysis of extracts of various cell lines, using CWC22 antibody (CAB13116) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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