Cell Biology Antibodies 6
Anti-CTRC Antibody (CAB16104)
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- SKU:
- CAB16104
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CTRC Antibody |
| Antibody SKU: | CAB16104 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-150 of human CTRC (NP_009203.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse pancreas |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-150 of human CTRC (NP_009203.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | VVGG EDAR PHSW PWQI SLQY LKND TWRH TCGG TLIA SNFV LTAA HCIS NTRT YRVA VGKN NLEV EDEE GSLF VGVD TIHV HKRW NALL LRND IALI KLAE HVEL SDTI QVAC LPEK DSLL P |
| Gene ID: | 11330 |
| Uniprot: | Q99895 |
| Cellular Location: | |
| Calculated MW: | 29kDa |
| Observed MW: | 30kDa |
| Synonyms: | CTRC, CLCR, ELA4 |
| Background: | This gene encodes a member of the peptidase S1 family. The encoded protein is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. |
| UniProt Protein Function: | CTRC: Has chymotrypsin-type protease activity and hypocalcemic activity. Genetic variations in CTRC can predispose to chronic pancreatitis by diminishing its protective trypsin-degrading activity. Belongs to the peptidase S1 family. Elastase subfamily. |
| UniProt Protein Details: | Protein type:Protease; EC 3.4.21.2 Chromosomal Location of Human Ortholog: 1p36.21 Molecular Function:peptidase activity; serine-type endopeptidase activity Biological Process: proteolysis Disease: Pancreatitis, Hereditary |
| NCBI Summary: | This gene encodes a member of the peptidase S1 family. The encoded protein is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q99895 |
| NCBI GenInfo Identifier: | 62526043 |
| NCBI Gene ID: | 11330 |
| NCBI Accession: | NP_009203.2 |
| UniProt Secondary Accession: | Q99895,O00765, Q9NUH5, A8K082, |
| UniProt Related Accession: | Q99895 |
| Molecular Weight: | 29,484 Da |
| NCBI Full Name: | chymotrypsin-C preproprotein |
| NCBI Synonym Full Names: | chymotrypsin C (caldecrin) |
| NCBI Official Symbol: | CTRC |
| NCBI Official Synonym Symbols: | CLCR; ELA4 |
| NCBI Protein Information: | chymotrypsin-C; caldecrin; elastase 4; elastase IV; serum calcium decreasing factor |
| UniProt Protein Name: | Chymotrypsin-C |
| UniProt Synonym Protein Names: | Caldecrin |
| Protein Family: | Chymotrypsin |
| UniProt Gene Name: | CTRC |
| UniProt Entry Name: | CTRC_HUMAN |
 | Western blot analysis of extracts of mouse pancreas, using CTRC antibody (CAB16104) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3min. |
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