Cell Biology Antibodies 6

Anti-CTRC Antibody (CAB16104)

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SKU:
CAB16104
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-CTRC Antibody
Antibody SKU:CAB16104
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 30-150 of human CTRC (NP_009203.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse pancreas
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 30-150 of human CTRC (NP_009203.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:VVGG EDAR PHSW PWQI SLQY LKND TWRH TCGG TLIA SNFV LTAA HCIS NTRT YRVA VGKN NLEV EDEE GSLF VGVD TIHV HKRW NALL LRND IALI KLAE HVEL SDTI QVAC LPEK DSLL P
Gene ID:11330
Uniprot:Q99895
Cellular Location:
Calculated MW:29kDa
Observed MW:30kDa
Synonyms:CTRC, CLCR, ELA4
Background:This gene encodes a member of the peptidase S1 family. The encoded protein is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
UniProt Protein Function:CTRC: Has chymotrypsin-type protease activity and hypocalcemic activity. Genetic variations in CTRC can predispose to chronic pancreatitis by diminishing its protective trypsin-degrading activity. Belongs to the peptidase S1 family. Elastase subfamily.
UniProt Protein Details:

Protein type:Protease; EC 3.4.21.2

Chromosomal Location of Human Ortholog: 1p36.21

Molecular Function:peptidase activity; serine-type endopeptidase activity

Biological Process: proteolysis

Disease: Pancreatitis, Hereditary

NCBI Summary:This gene encodes a member of the peptidase S1 family. The encoded protein is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
UniProt Code:Q99895
NCBI GenInfo Identifier:62526043
NCBI Gene ID:11330
NCBI Accession:NP_009203.2
UniProt Secondary Accession:Q99895,O00765, Q9NUH5, A8K082,
UniProt Related Accession:Q99895
Molecular Weight:29,484 Da
NCBI Full Name:chymotrypsin-C preproprotein
NCBI Synonym Full Names:chymotrypsin C (caldecrin)
NCBI Official Symbol:CTRC  
NCBI Official Synonym Symbols:CLCR; ELA4  
NCBI Protein Information:chymotrypsin-C; caldecrin; elastase 4; elastase IV; serum calcium decreasing factor
UniProt Protein Name:Chymotrypsin-C
UniProt Synonym Protein Names:Caldecrin
Protein Family:Chymotrypsin
UniProt Gene Name:CTRC  
UniProt Entry Name:CTRC_HUMAN
Anti-CTRC Antibody (CAB16104)Western blot analysis of extracts of mouse pancreas, using CTRC antibody (CAB16104) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3min.
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