Description
| Product Name: | CTNNA3 Rabbit mAb |
| Product Code: | CAB19282 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | CTNNA3, ARVD13, VR22, catenin alpha-3 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human CTNNA3. |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | PC-3, Mouse testis, Mouse brain, Mouse heart, Rat testis, Rat brain |
| Immunogen: | Recombinant protein of human CTNNA3. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 29119 |
| Uniprot: | Q9UI47 |
| Cellular Location: | Cytoplasm, cytoskeleton |
| Calculated MW: | 100kDa |
| Observed MW: | 100KDa |
| UniProt Protein Function: | CTNNA3: May be involved in formation of stretch-resistant cell- cell adhesion complexes. Belongs to the vinculin/alpha-catenin family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell adhesion Chromosomal Location of Human Ortholog: 10q22.2 Cellular Component: cytoskeleton; lamellipodium; cytoplasm; fascia adherens Molecular Function:actin filament binding; protein binding; cadherin binding Biological Process: cell-cell adhesion Disease: Arrhythmogenic Right Ventricular Dysplasia, Familial, 13 |
| NCBI Summary: | This gene encodes a protein that belongs to the vinculin/alpha-catenin family. The encoded protein plays a role in cell-cell adhesion in muscle cells. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia, familial 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] |
| UniProt Code: | Q9UI47 |
| NCBI GenInfo Identifier: | 78099215 |
| NCBI Gene ID: | 29119 |
| NCBI Accession: | Q9UI47.2 |
| UniProt Secondary Accession: | Q9UI47,Q5VSR2, Q6P056, |
| UniProt Related Accession: | Q9UI47 |
| Molecular Weight: | 57,332 Da |
| NCBI Full Name: | Catenin alpha-3 |
| NCBI Synonym Full Names: | catenin (cadherin-associated protein), alpha 3 |
| NCBI Official Symbol: | CTNNA3 |
| NCBI Official Synonym Symbols: | VR22; ARVD13 |
| NCBI Protein Information: | catenin alpha-3; alpha-T-catenin; alpha-catenin-like protein |
| UniProt Protein Name: | Catenin alpha-3 |
| UniProt Synonym Protein Names: | Alpha T-catenin; Cadherin-associated protein |
| Protein Family: | Catenin |
| UniProt Gene Name: | CTNNA3 |
| UniProt Entry Name: | CTNA3_HUMAN |