Cell Biology Antibodies 7
Anti-CTNNA3 Antibody (CAB16519)
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- SKU:
- CAB16519
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CTNNA3 Antibody |
| Antibody SKU: | CAB16519 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human CTNNA3 (NP_001278062.1). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | LO2, 293T, Mouse spleen, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human CTNNA3 (NP_001278062.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MKST QRRE KQGS MSAE TPIT LNID PQDL QVQT FTVE KLLE PLII QVTT LVNC PQNP SSRK KGRS KRAS VLLA SVEE ATWN LLDK GEKI AQEA TVLK DELT ASLE EVRK ESEA LKVS AERF TDDP CFLP KREA VVQA ARAL LAAV TRLL ILAD MIDV MCLL QHVS AFQR TFES LKNV ANKS DLQK TYQK LGKE LENL DYLA FKRQ QDLK SPNQ RDEI AGAR ASLK ENSP LLHS ICSA CLEH |
| Gene ID: | 29119 |
| Uniprot: | Q9UI47 |
| Cellular Location: | Cytoplasm, cytoskeleton |
| Calculated MW: | 57kDa/99kDa |
| Observed MW: | 120kDa |
| Synonyms: | CTNNA3, ARVD13, VR22 |
| Background: | This gene encodes a protein that belongs to the vinculin/alpha-catenin family. The encoded protein plays a role in cell-cell adhesion in muscle cells. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia, familial 13. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | CTNNA3: May be involved in formation of stretch-resistant cell- cell adhesion complexes. Belongs to the vinculin/alpha-catenin family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell adhesion Chromosomal Location of Human Ortholog: 10q22.2 Cellular Component: cytoskeleton; lamellipodium; cytoplasm; fascia adherens Molecular Function:actin filament binding; protein binding; cadherin binding Biological Process: cell-cell adhesion Disease: Arrhythmogenic Right Ventricular Dysplasia, Familial, 13 |
| NCBI Summary: | This gene encodes a protein that belongs to the vinculin/alpha-catenin family. The encoded protein plays a role in cell-cell adhesion in muscle cells. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia, familial 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] |
| UniProt Code: | Q9UI47 |
| NCBI GenInfo Identifier: | 78099215 |
| NCBI Gene ID: | 29119 |
| NCBI Accession: | Q9UI47.2 |
| UniProt Secondary Accession: | Q9UI47,Q5VSR2, Q6P056, |
| UniProt Related Accession: | Q9UI47 |
| Molecular Weight: | 57,332 Da |
| NCBI Full Name: | Catenin alpha-3 |
| NCBI Synonym Full Names: | catenin (cadherin-associated protein), alpha 3 |
| NCBI Official Symbol: | CTNNA3 |
| NCBI Official Synonym Symbols: | VR22; ARVD13 |
| NCBI Protein Information: | catenin alpha-3; alpha-T-catenin; alpha-catenin-like protein |
| UniProt Protein Name: | Catenin alpha-3 |
| UniProt Synonym Protein Names: | Alpha T-catenin; Cadherin-associated protein |
| Protein Family: | Catenin |
| UniProt Gene Name: | CTNNA3 |
| UniProt Entry Name: | CTNA3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CTNNA3 antibody (CAB16519) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
 | Immunohistochemistry of paraffin-embedded Mouse testis using CTNNA3 Rabbit pAb (CAB16519) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded Rat testis using CTNNA3 Rabbit pAb (CAB16519) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded Human liver cancer using CTNNA3 Rabbit pAb (CAB16519) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of L929 cells using CTNNA3 antibody (CAB16519) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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