Anti-CTIP2/BCL11B Antibody (CAB19804)
- SKU:
- CAB19804
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ATL1
- Synonyms:
- ATL1-alpha
- Synonyms:
- ATL1-beta
- Synonyms:
- ATL1-delta
- Synonyms:
- ATL1-gamma
- Synonyms:
- CTIP-2
- Synonyms:
- CTIP2
- Synonyms:
- IMD49
- Synonyms:
- RIT1
- Synonyms:
- ZNF856B
- Synonyms:
- hRIT1-alpha
Description
| Product Name: | CTIP2/BCL11B Rabbit mAb |
| Product Code: | CAB19804 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | ATL1, ATL1-alpha, ATL1-beta, ATL1-delta, ATL1-gamma, CTIP-2, CTIP2, IMD49, RIT1, ZNF856B, hRIT1-alpha |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human CTIP2/BCL11B |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Jurkat, Raji, SH-SY5Y |
| Immunogen: | A synthesized peptide derived from human CTIP2/BCL11B |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 64919 |
| Uniprot: | Q9C0K0 |
| Calculated MW: | 140kDa |
| Observed MW: | 120-130KDa |
| UniProt Protein Function: | Tumor-suppressor protein involved in T-cell lymphomas. May function on the P53-signaling pathway. May be a key regulator of both differentiation and survival during thymocyte development. Repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element. |
| NCBI Summary: | This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2013] |
| UniProt Code: | Q9C0K0 |
| NCBI GenInfo Identifier: | 44887723 |
| NCBI Gene ID: | 64919 |
| NCBI Accession: | Q9C0K0.1 |
| UniProt Secondary Accession: | Q9C0K0,Q9H162, |
| UniProt Related Accession: | Q9C0K0 |
| Molecular Weight: | 88,476 Da |
| NCBI Full Name: | B-cell lymphoma/leukemia 11B |
| NCBI Synonym Full Names: | B-cell CLL/lymphoma 11B |
| NCBI Official Symbol: | BCL11B |
| NCBI Official Synonym Symbols: | ATL1; RIT1; CTIP2; CTIP-2; ZNF856B; ATL1-beta; ATL1-alpha; ATL1-delta; ATL1-gamma; hRIT1-alpha |
| NCBI Protein Information: | B-cell lymphoma/leukemia 11B |
| UniProt Protein Name: | B-cell lymphoma/leukemia 11B |
| UniProt Synonym Protein Names: | B-cell CLL/lymphoma 11B; COUP-TF-interacting protein 2; Radiation-induced tumor suppressor gene 1 protein; hRit1 |
| Protein Family: | B-cell lymphoma/leukemia |
| UniProt Gene Name: | BCL11B |
| UniProt Entry Name: | BC11B_HUMAN |
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