Cell Biology Antibodies 14

Anti-CTF1 Antibody (CAB18169)

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SKU:
CAB18169
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-CTF1 Antibody
Antibody SKU:CAB18169
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant protein of human CTF1.
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:
Immunogen:Recombinant protein of human CTF1.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:1489
Uniprot:Q16619
Cellular Location:
Calculated MW:
Observed MW:Refer to figures
Synonyms:CT-1, CT1, CTF1
Background:
UniProt Protein Function:CTF1: Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor. Belongs to the IL-6 superfamily. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Cytokine

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: extracellular space; extracellular region

Molecular Function:leukemia inhibitory factor receptor binding; cytokine activity

Biological Process: cell proliferation; nervous system development; muscle development; cell-cell signaling; leukemia inhibitory factor signaling pathway; positive regulation of cell proliferation; neuron development

NCBI Summary:The protein encoded by this gene is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
UniProt Code:Q16619
NCBI GenInfo Identifier:2498265
NCBI Gene ID:1489
NCBI Accession:Q16619.1
UniProt Secondary Accession:Q16619,Q5U5Y7, A8MVX4,
UniProt Related Accession:Q16619
Molecular Weight:21,098 Da
NCBI Full Name:Cardiotrophin-1
NCBI Synonym Full Names:cardiotrophin 1
NCBI Official Symbol:CTF1  
NCBI Official Synonym Symbols:CT1; CT-1  
NCBI Protein Information:cardiotrophin-1; cardiophin 1
UniProt Protein Name:Cardiotrophin-1
Protein Family:Cardiotrophin
UniProt Gene Name:CTF1  
UniProt Entry Name:CTF1_HUMAN
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system_update_altDatasheetHuman Cardiotrophin/CTF1 Recombinant Protein Cardiotrophin-1, also known as CT-1 and CTF1, is a member of the IL-6 superfamily. It is a sreted cytokine that is expressed