Cell Death Antibodies 2

Anti-CSRNP2 Antibody (CAB7388)

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SKU:
CAB7388
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Death

Description

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Antibody Name:Anti-CSRNP2 Antibody
Antibody SKU:CAB7388
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 324-543 of human CSRNP2 (NP_110436.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 324-543 of human CSRNP2 (NP_110436.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:VMHL QSAE ELER LKAE EDSS GSSA SLDS SIES LGVC ILEE PLAV PEEL CPGL TAPI LIQA QLPP GSSV LCFT ENSD HPTA STVN SPSY LNSG PLVY YQVE QRPV LGVK GEPG TEEG SASF PKEK DLNV FSLP VTSL VACS STDP AALC KSEV GKTP TLEA LLPE DCNP EEPE NEDF HPSW SPSS LPFR TDNE EGCG MVKT SQQN EDRP PEDS SLEL PLAV
Gene ID:81566
Uniprot:Q9H175
Cellular Location:Nucleus
Calculated MW:59kDa
Observed MW:Refer to figures
Synonyms:CSRNP2, C12orf2, C12orf22, FAM130A1, PPP1R72, TAIP-12
Background:The protein encoded by this gene belongs to the CSRNP family of nuclear proteins that share conserved regions, including cysteine- and serine- rich regions, a basic domain, a transcriptional activation domain, and bind the sequence 'AGAGTG', thus have the hallmark of transcription factors. Studies in mice suggest that these genes may have redundant functions. Alternatively spliced transcript variants have been found for this gene.
UniProt Protein Function:TAIP12: Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity. May play a role in apoptosis. Belongs to the AXUD1 family.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 12q13.11-q13.12

Cellular Component: nucleus

Molecular Function:phosphatase binding; protein binding; transcription factor activity

Biological Process: positive regulation of transcription from RNA polymerase II promoter

NCBI Summary:The protein encoded by this gene belongs to the CSRNP family of nuclear proteins that share conserved regions, including cysteine- and serine- rich regions, a basic domain, a transcriptional activation domain, and bind the sequence 'AGAGTG', thus have the hallmark of transcription factors. Studies in mice suggest that these genes may have redundant functions. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]
UniProt Code:Q9H175
NCBI GenInfo Identifier:71153583
NCBI Gene ID:81566
NCBI Accession:Q9H175.1
UniProt Related Accession:Q9H175
Molecular Weight:59,591 Da
NCBI Full Name:Cysteine/serine-rich nuclear protein 2
NCBI Synonym Full Names:cysteine and serine rich nuclear protein 2
NCBI Official Symbol:CSRNP2  
NCBI Official Synonym Symbols:C12orf2; PPP1R72; TAIP-12; C12orf22; FAM130A1  
NCBI Protein Information:cysteine/serine-rich nuclear protein 2
UniProt Protein Name:Cysteine/serine-rich nuclear protein 2
UniProt Synonym Protein Names:Protein FAM130A1; TGF-beta-induced apoptosis protein 12; TAIP-12
Protein Family:Cysteine/serine-rich nuclear protein
UniProt Gene Name:CSRNP2  
UniProt Entry Name:CSRN2_HUMAN
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