UniProt Protein Function: | AXUD1: Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity. May have a tumor-suppressor function. May play a role in apoptosis. Belongs to the AXUD1 family. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 3p22 Cellular Component: nucleus Molecular Function:sequence-specific DNA binding; transcription factor activity Biological Process: transcription, DNA-dependent; apoptosis; skeletal morphogenesis; platelet-derived growth factor receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; palate development; post-embryonic development |
NCBI Summary: | This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q96S65 |
NCBI GenInfo Identifier: | 308153432 |
NCBI Gene ID: | 64651 |
NCBI Accession: | Q96S65.2 |
UniProt Secondary Accession: | Q96S65,Q69YY5, |
UniProt Related Accession: | Q96S65 |
Molecular Weight: | 589 |
NCBI Full Name: | Cysteine/serine-rich nuclear protein 1 |
NCBI Synonym Full Names: | cysteine-serine-rich nuclear protein 1 |
NCBI Official Symbol: | CSRNP1 |
NCBI Official Synonym Symbols: | AXUD1; URAX1; TAIP-3; CSRNP-1; FAM130B |
NCBI Protein Information: | cysteine/serine-rich nuclear protein 1; AXIN1 up-regulated 1; axin-1 up-regulated gene 1 protein; TGF-beta induced apoptosis protein 3; TGF-beta-induced apoptosis protein 3 |
UniProt Protein Name: | Cysteine/serine-rich nuclear protein 1 |
UniProt Synonym Protein Names: | Axin-1 up-regulated gene 1 protein; Protein URAX1; TGF-beta-induced apoptosis protein 3; TAIP-3 |
Protein Family: | Cysteine/serine-rich nuclear protein |
UniProt Gene Name: | CSRNP1 |
UniProt Entry Name: | CSRN1_HUMAN |