Metabolism Antibodies 1
Anti-CSNK1G3 Antibody (CAB13013)
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- SKU:
- CAB13013
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Description
| Antibody Name: | Anti-CSNK1G3 Antibody |
| Antibody SKU: | CAB13013 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 304-423 of human CSNK1G3 (NP_001026982.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse eye, Mouse brain, Rat heart |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 304-423 of human CSNK1G3 (NP_001026982.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LRKL FTDL FDRK GYMF DYEY DWIG KQLP TPVG AVQQ DPAL SSNR EAHQ HRDK MQQS KNQV VSST NGEL NTDD PTAG RSNA PITA PTEV EVMD ETNC QKVL NMWC CCFF KRRK RKTI QRHK |
| Gene ID: | 1456 |
| Uniprot: | Q9Y6M4 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 36kDa/40kDa/48kDa/49kDa/51kDa/52kDa |
| Observed MW: | 51kDa |
| Synonyms: | CSNK1G3, CKI-gamma 3, CSNK1G3L, CKI-gamma3 |
| Background: | This gene encodes a member of a family of serine/threonine protein kinases that phosphorylate caseins and other acidic proteins. A related protein in the African clawed frog participates in the transmission of Wnt/beta-catenin signaling. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| UniProt Protein Function: | CK1G3: Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate. Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Protein kinase, CK1; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; CK1 group; CK1 family Chromosomal Location of Human Ortholog: 5q23 Cellular Component: cytoplasm; nucleus Molecular Function:protein kinase activity; protein serine/threonine kinase activity Biological Process: endocytosis; peptidyl-serine phosphorylation; protein modification process; regulation of cell shape; signal transduction; Wnt receptor signaling pathway |
| NCBI Summary: | This gene encodes a member of a family of serine/threonine protein kinases that phosphorylate caseins and other acidic proteins. A related protein in the African clawed frog participates in the transmission of Wnt/beta-catenin signaling. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] |
| UniProt Code: | Q9Y6M4 |
| NCBI GenInfo Identifier: | 47117932 |
| NCBI Gene ID: | 1456 |
| NCBI Accession: | Q9Y6M4.2 |
| UniProt Secondary Accession: | Q9Y6M4,Q86WZ7, Q9Y6M3, A8K040, B4DSH2, B7Z9Q4, E7EVD0 |
| UniProt Related Accession: | Q9Y6M4 |
| Molecular Weight: | 36,492 Da |
| NCBI Full Name: | Casein kinase I isoform gamma-3 |
| NCBI Synonym Full Names: | casein kinase 1 gamma 3 |
| NCBI Official Symbol: | CSNK1G3 |
| NCBI Official Synonym Symbols: | CSNK1G3L; CKI-gamma 3 |
| NCBI Protein Information: | casein kinase I isoform gamma-3 |
| UniProt Protein Name: | Casein kinase I isoform gamma-3 |
| Protein Family: | Casein kinase |
| UniProt Gene Name: | CSNK1G3 |
| UniProt Entry Name: | KC1G3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CSNK1G3 antibody (CAB13013) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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