Cell Biology Antibodies 6
Anti-CSNK1D Antibody (CAB15661)
- SKU:
- CAB15661
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CSNK1D Antibody |
| Antibody SKU: | CAB15661 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CSNK1D (NP_620693.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Rat |
| Positive Samples: | Rat heart, Rat brain |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CSNK1D (NP_620693.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | TYLN FCRS LRFD DKPD YSYL RQLF RNLF HRQG FSYD YVFD WNML KFGA SRAA DDAE RERR DREE RLRH SRNP ATRG LPST ASGR LRGT QEVA PPTP LTPT S |
| Gene ID: | 1453 |
| Uniprot: | P48730 |
| Cellular Location: | Cell membrane, Cytoplasm, Golgi apparatus, Nucleus, centrosome, cytoskeleton, microtubule organizing center, perinuclear region, spindle |
| Calculated MW: | 46kDa/47kDa |
| Observed MW: | 47kDa |
| Synonyms: | CSNK1D, ASPS, CKIdelta, FASPS2, HCKID |
| Background: | This gene is a member of the casein kinase I (CKI) gene family whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein may also be involved in the regulation of apoptosis, circadian rhythm, microtubule dynamics, chromosome segregation, and p53-mediated effects on growth. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Three transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | CK1D: an ubiquitous protein kinase of the CK1 family. Enriched at the centrosomes in interphase and at the spindle during mitosis. May play a role in cell cycle progression. Two splice variant isoforms have been described. |
| UniProt Protein Details: | Protein type:Protein kinase, CK1; EC 2.7.11.26; Kinase, protein; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); CK1 group; CK1 family Chromosomal Location of Human Ortholog: 17q25 Cellular Component: centrosome; cytosol; ER-Golgi intermediate compartment membrane; Golgi apparatus; nucleoplasm; nucleus; perinuclear region of cytoplasm; plasma membrane; spindle; spindle microtubule Molecular Function:protein binding; protein kinase activity; protein serine/threonine kinase activity Biological Process: circadian regulation of gene expression; COPII coating of Golgi vesicle; DNA repair; endocytosis; G2/M transition of mitotic cell cycle; Golgi organization and biogenesis; microtubule nucleation; peptidyl-serine phosphorylation; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of protein amino acid phosphorylation; protein amino acid phosphorylation; protein localization in Golgi apparatus; regulation of cell shape; regulation of circadian rhythm; rRNA processing; sensory cilium biogenesis; signal transduction; spindle assembly Disease: Advanced Sleep Phase Syndrome, Familial, 2 |
| NCBI Summary: | This gene is a member of the casein kinase I (CKI) gene family whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein may also be involved in the regulation of apoptosis, circadian rhythm, microtubule dynamics, chromosome segregation, and p53-mediated effects on growth. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014] |
| UniProt Code: | P48730 |
| NCBI GenInfo Identifier: | 27923980 |
| NCBI Gene ID: | 1453 |
| NCBI Accession: | P48730.2 |
| UniProt Secondary Accession: | P48730,Q96KZ6, Q9BTN5, A2I2P2, |
| UniProt Related Accession: | P48730 |
| Molecular Weight: | 46,832 Da |
| NCBI Full Name: | Casein kinase I isoform delta |
| NCBI Synonym Full Names: | casein kinase 1 delta |
| NCBI Official Symbol: | CSNK1D |
| NCBI Official Synonym Symbols: | ASPS; HCKID; FASPS2; CKIdelta |
| NCBI Protein Information: | casein kinase I isoform delta |
| UniProt Protein Name: | Casein kinase I isoform delta |
| UniProt Synonym Protein Names: | Tau-protein kinase CSNK1D (EC:2.7.11.26) |
| Protein Family: | Casein kinase |
| UniProt Gene Name: | CSNK1D |
| UniProt Entry Name: | KC1D_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CSNK1D antibody (CAB15661) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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