Cell Biology Antibodies 7

Anti-CRTAC1 Antibody (CAB16541)

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SKU:
CAB16541
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-CRTAC1 Antibody
Antibody SKU:CAB16541
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 312-661 of human CRTAC1 (NP_060528.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 312-661 of human CRTAC1 (NP_060528.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:NWNG PHRL YLQM STHG KVRF RDIA SPKF SMPS PVRT VITA DFDN DQEL EIFF NNIA YRSS SANR LFRV IRRE HGDP LIEE LNPG DALE PEGR GTGG VVTD FDGD GMLD LILS HGES MAQP LSVF RGNQ GFNN NWLR VVPR TRFG AFAR GAKV VLYT KKSG AHLR IIDG GSGY LCEM EPVA HFGL GKDE ASSV EVTW PDGK MVSR NVAS GEMN SVLE ILYP RDED TLQD PAPL ECGQ GFSQ QENG HCMD TNEC IQFP FVCP RDKP VCVN TYGS YRCR TNKK CSRG YEPN EDGT ACVG TLGQ SPGP RPTT PTAA AATA AAAA AAGA ATAA PVLV DGDL NLGS VVKE SCEP SC
Gene ID:55118
Uniprot:Q9NQ79
Cellular Location:Secreted, extracellular matrix, extracellular space
Calculated MW:68kDa/70kDa/71kDa
Observed MW:71kDa
Synonyms:CRTAC1, ASPIC, ASPIC1, CEP-68
Background:This gene encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:CRTAC1: a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
UniProt Protein Details:

Protein type:Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 10q22

Molecular Function:protein binding

NCBI Summary:This gene encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
UniProt Code:Q9NQ79
NCBI GenInfo Identifier:50400672
NCBI Gene ID:55118
NCBI Accession:Q9NQ79.2
UniProt Secondary Accession:Q9NQ79,Q5T4F8, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46 B1ALN4,
UniProt Related Accession:Q9NQ79
Molecular Weight:68,059 Da
NCBI Full Name:Cartilage acidic protein 1
NCBI Synonym Full Names:cartilage acidic protein 1
NCBI Official Symbol:CRTAC1  
NCBI Official Synonym Symbols:ASPIC; ASPIC1; CEP-68  
NCBI Protein Information:cartilage acidic protein 1
UniProt Protein Name:Cartilage acidic protein 1
UniProt Synonym Protein Names:68 kDa chondrocyte-expressed protein; CEP-68; ASPIC
Protein Family:Cartilage acidic protein
UniProt Gene Name:CRTAC1  
UniProt Entry Name:CRAC1_HUMAN
Anti-CRTAC1 Antibody (CAB16541)Western blot analysis of extracts of mouse brain, using CRTAC1 antibody (CAB16541) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
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