Cell Biology Antibodies 11
Anti-CRIP1 Antibody (CAB7548)
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- SKU:
- CAB7548
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CRIP1 Antibody |
| Antibody SKU: | CAB7548 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-77 of human CRIP1 (NP_001302.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Mouse lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-77 of human CRIP1 (NP_001302.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MPKC PKCN KEVY FAER VTSL GKDW HRPC LKCE KCGK TLTS GGHA EHEG KPYC NHPC YAAM FGPK GFGR GGAE SHTF K |
| Gene ID: | 1396 |
| Uniprot: | P50238 |
| Cellular Location: | |
| Calculated MW: | 8kDa |
| Observed MW: | 13kDa |
| Synonyms: | CRIP1, CRHP, CRIP, CRP-1, CRP1 |
| Background: |
| UniProt Protein Function: | CRIP1: a LIM protein which is developmentally regulated in heart. May have a role in zinc absorption and may function as an intracellular zinc transport protein. The CRIP1 gene is hypomethylated in prostate cancer. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 14q32.33 Cellular Component: cytoplasm Molecular Function:AT DNA binding; DNA bending activity; peptide binding; zinc ion binding Biological Process: cell proliferation; DNA damage response, signal transduction resulting in induction of apoptosis; heart development; immune response; regulation of gene expression; response to organic substance; response to zinc ion |
| NCBI Summary: | Cysteine-rich intestinal protein (CRIP) belongs to the LIM/double zinc finger protein family, members of which include cysteine- and glycine-rich protein-1 (CSRP1; MIM 123876), rhombotin-1 (RBTN1; MIM 186921), rhombotin-2 (RBTN2; MIM 180385), and rhombotin-3 (RBTN3; MIM 180386). CRIP may be involved in intestinal zinc transport (Hempe and Cousins, 1991 [PubMed 1946385]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | P50238 |
| NCBI GenInfo Identifier: | 20981688 |
| NCBI Gene ID: | 1396 |
| NCBI Accession: | P50238.3 |
| UniProt Secondary Accession: | P50238,Q13628, Q53XY7, Q96J34, H3BPI2, |
| UniProt Related Accession: | P50238 |
| Molecular Weight: | 8,533 Da |
| NCBI Full Name: | Cysteine-rich protein 1 |
| NCBI Synonym Full Names: | cysteine rich protein 1 |
| NCBI Official Symbol: | CRIP1 |
| NCBI Official Synonym Symbols: | CRHP; CRIP; CRP1; CRP-1 |
| NCBI Protein Information: | cysteine-rich protein 1 |
| UniProt Protein Name: | Cysteine-rich protein 1 |
| UniProt Synonym Protein Names: | Cysteine-rich heart protein; CRHP; hCRHP; Cysteine-rich intestinal protein; CRIP |
| Protein Family: | Cysteine-rich protein |
| UniProt Gene Name: | CRIP1 |
| UniProt Entry Name: | CRIP1_HUMAN |
 | Western blot analysis of extracts of mouse lung, using CRIP1 antibody (CAB7548) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 5s. |
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