Immunology Antibodies 2

Anti-CRCP Antibody (CAB4657)

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SKU:
CAB4657
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
CRCP
Synonyms:
CGRP-RCP
Synonyms:
CGRPRCP
Synonyms:
RCP
Synonyms:
RCP9
Research Area:
Immunology

Description

Product Name:CRCP Rabbit pAb
Product Code:CAB4657
Size:20uL, 50uL, 100uL
Synonyms:CRCP, CGRP-RCP, CGRPRCP, RCP, RCP9
Applications:WB, IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of human CRCP (NP_001035737.1).
Applications:WB, IHC
Recommended Dilutions:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:U-87MG, HeLa, Jurkat, Mouse testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of human CRCP (NP_001035737.1).
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MEVK DANS ALLS NYET LKYI SKTP CRHQ SPEI VREF LTAL KSHK LTKA EKLQ LLNH RPVT AVEI QLMV EESE ERLT EEQI EALL HTVT SILP AEPE AEQK KNTN SNVA MDEE DPA
Gene ID:27297
Uniprot:O75575
Cellular Location:Cell membrane, Cytoplasmic side, Nucleus, Peripheral membrane protein
Calculated MW:8kDa/13kDa/15kDa/16kDa
Observed MW:20kDa
UniProt Protein Function:CGRP-RCP: an ubiquitous coupling protein for the calcitonin gene-related peptide (CGRP) and adrenomedullin receptors. Modulates ligand responsiveness in a variety of tissues. Two splice-variant isoforms have been described.
UniProt Protein Details:

Protein type:Adaptor/scaffold

Chromosomal Location of Human Ortholog: 7q11.21

Cellular Component: nucleoplasm; DNA-directed RNA polymerase III complex; plasma membrane; acrosome; cytosol

Molecular Function:calcitonin gene-related polypeptide receptor activity; DNA-directed RNA polymerase activity; nucleotide binding

Biological Process: transcription from RNA polymerase III promoter; transcription initiation from RNA polymerase III promoter; termination of RNA polymerase III transcription; neuropeptide signaling pathway; positive regulation of interferon type I production; innate immune response; gene expression; defense response to virus; RNA elongation from RNA polymerase III promoter

NCBI Summary:This gene encodes a membrane protein that functions as part of a receptor complex for a small neuropeptide that increases intracellular cAMP levels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
UniProt Code:O75575
NCBI GenInfo Identifier:20532033
NCBI Gene ID:27297
NCBI Accession:O75575.1
UniProt Secondary Accession:O75575,Q3KRA3, Q5HYF1, Q8IXL4, A8MUZ4, A8MW23, B2R4H4 B4E198,
UniProt Related Accession:O75575
Molecular Weight:148
NCBI Full Name:DNA-directed RNA polymerase III subunit RPC9
NCBI Synonym Full Names:CGRP receptor component
NCBI Official Symbol:CRCP  
NCBI Official Synonym Symbols:RCP; RCP9; CGRPRCP; CGRP-RCP  
NCBI Protein Information:DNA-directed RNA polymerase III subunit RPC9; RNA polymerase III subunit C9; CGRP-receptor component protein; calcitonin gene-related peptide-receptor component protein
UniProt Protein Name:DNA-directed RNA polymerase III subunit RPC9
UniProt Synonym Protein Names:Calcitonin gene-related peptide-receptor component protein; CGRP-RCP; CGRP-receptor component protein; CGRPRCP; HsC17
Protein Family:DNA-directed RNA polymerase
UniProt Gene Name:CRCP  
UniProt Entry Name:RPC9_HUMAN
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