Cell Biology Antibodies 15
Anti-CRB3 Antibody (CAB17810)
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- SKU:
- CAB17810
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CRB3 Antibody |
| Antibody SKU: | CAB17810 |
| Antibody Size: | 20uL, 50 uL |
| Application: | IHC |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-123 of human CRB3 (NP_777377.1). |
| Application: | IHC |
| Recommended Dilution: | IHC 1:50 - 1:100 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-123 of human CRB3 (NP_777377.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MANP GLGL LLAL GLPF LLAR WGRA WGQI QTTS ANEN STVL PSST SSSS DGNL RPEA ITAI IVVF SLLA ALLL AVGL ALLV RKLR EKRQ TEGT YRPS SEEQ FSHA AEAR APQD SKET VQGC LPI |
| Gene ID: | 92359 |
| Uniprot: | Q9BUF7 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | CRB3 |
| Background: | This gene encodes a member of the Crumbs family of proteins. This gene is widely expressed in epithelial tissues where the encoded protein isoforms play various roles such as the control of cytokinesis and ciliogenesis or the formation of tight junctions. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016] |
| UniProt Protein Function: | CRB3: Involved in the establishment of cell polarity in mammalian epithelial cells. Regulates the morphogenesis of tight junctions. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Motility/polarity/chemotaxis; Cell adhesion Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: cell junction; plasma membrane Molecular Function:protein binding; protein domain specific binding; SH3 domain binding |
| NCBI Summary: | This gene encodes a member of the Crumbs family of proteins. This gene is widely expressed in epithelial tissues where the encoded protein isoforms play various roles such as the control of cytokinesis and ciliogenesis or the formation of tight junctions. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016] |
| UniProt Code: | Q9BUF7 |
| NCBI GenInfo Identifier: | 67460584 |
| NCBI Gene ID: | 92359 |
| NCBI Accession: | Q9BUF7.3 |
| UniProt Secondary Accession: | Q9BUF7,Q8N0V8, Q8WVA0, A8KA91, D6W643, |
| UniProt Related Accession: | Q9BUF7 |
| Molecular Weight: | 13,113 Da |
| NCBI Full Name: | Protein crumbs homolog 3 |
| NCBI Synonym Full Names: | crumbs 3, cell polarity complex component |
| NCBI Official Symbol: | CRB3 |
| NCBI Protein Information: | protein crumbs homolog 3 |
| UniProt Protein Name: | Protein crumbs homolog 3 |
| Protein Family: | Protein crumbs |
| UniProt Gene Name: | CRB3 |
| UniProt Entry Name: | CRUM3_HUMAN |
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