Signal Transduction Antibodies 1

Anti-CRABP1 Antibody (CAB12707)

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SKU:
CAB12707
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-CRABP1 Antibody
Antibody SKU:CAB12707
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-137 of human CRABP1 (NP_004369.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-137 of human CRABP1 (NP_004369.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MPNF AGTW KMRS SENF DELL KALG VNAM LRKV AVAA ASKP HVEI RQDG DQFY IKTS TTVR TTEI NFKV GEGF EEET VDGR KCRS LATW ENEN KIHC TQTL LEGD GPKT YWTR ELAN DELI LTFG ADDV VCTR IYVR E
Gene ID:1381
Uniprot:P29762
Cellular Location:Cytoplasm
Calculated MW:15kDa
Observed MW:14kDa
Synonyms:CRABP1, CRABP, CRABP-I, CRABPI, RBP5
Background:This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue.
UniProt Protein Function:CRABP1: Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 15q25.1

Cellular Component: cytosol

Molecular Function:protein binding; retinoid binding

Biological Process: multicellular organismal development; signal transduction

NCBI Summary:This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue. [provided by RefSeq, Jul 2008]
UniProt Code:P29762
NCBI GenInfo Identifier:266904
NCBI Gene ID:1381
NCBI Accession:P29762.2
UniProt Secondary Accession:P29762,Q6IAY7, Q8WTV5,
UniProt Related Accession:P29762
Molecular Weight:16kDa
NCBI Full Name:Cellular retinoic acid-binding protein 1
NCBI Synonym Full Names:cellular retinoic acid binding protein 1
NCBI Official Symbol:CRABP1  
NCBI Official Synonym Symbols:RBP5; CRABP; CRABPI; CRABP-I  
NCBI Protein Information:cellular retinoic acid-binding protein 1
UniProt Protein Name:Cellular retinoic acid-binding protein 1
UniProt Synonym Protein Names:Cellular retinoic acid-binding protein I; CRABP-I
Protein Family:Cellular retinoic acid-binding protein
UniProt Gene Name:CRABP1  
Anti-CRABP1 Antibody (CAB12707)Western blot analysis of extracts of mouse testis, using CRABP1 antibody (CAB12707) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
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