Cell Biology Antibodies 2
Anti-CPVL Antibody (CAB12370)
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- SKU:
- CAB12370
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CPVL Antibody |
| Antibody SKU: | CAB12370 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 127-476 of human CPVL (NP_061902.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Rat |
| Positive Samples: | 293T, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 127-476 of human CPVL (NP_061902.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | YVVT SNMT LRDR DFPW TTTL SMLY IDNP VGTG FSFT DDTH GYAV NEDD VARD LYSA LIQF FQIF PEYK NNDF YVTG ESYA GKYV PAIA HLIH SLNP VREV KINL NGIA IGDG YSDP ESII GGYA EFLY QIGL LDEK QKKY FQKQ CHEC IEHI RKQN WFEA FEIL DKLL DGDL TSDP SYFQ NVTG CSNY YNFL RCTE PEDQ LYYV KFLS LPEV RQAI HVGN QTFN DGTI VEKY LRED TVQS VKPW LTEI MNNY KVLI YNGQ LDII VAAA LTER SLMG MDWK GSQE YKKA EKKV WKIF KSDS EVAG YIRQ AGDF HQVI IRGG GHIL PYDQ PLRA FDMI NRFI YGKG WDPY VG |
| Gene ID: | 54504 |
| Uniprot: | Q9H3G5 |
| Cellular Location: | |
| Calculated MW: | 54kDa |
| Observed MW: | 54kDa |
| Synonyms: | CPVL, HVLP |
| Background: | The protein encoded by this gene is a carboxypeptidase and bears strong sequence similarity to serine carboxypeptidases. Carboxypeptidases are a large class of proteases that act to cleave a single amino acid from the carboxy termini of proteins or peptides. The exact function of this protein, however, has not been determined. At least two alternatively spliced transcripts which encode the same protein have been observed. |
| UniProt Protein Function: | CPVL: May be involved in the digestion of phagocytosed particles in the lysosome, participation in an inflammatory protease cascade, and trimming of peptides for antigen presentation. Belongs to the peptidase S10 family. |
| UniProt Protein Details: | Protein type:Secreted; Protease; Secreted, signal peptide; EC 3.4.16.- Chromosomal Location of Human Ortholog: 7p15.1 Molecular Function:serine carboxypeptidase activity Biological Process: proteolysis |
| NCBI Summary: | The protein encoded by this gene is a carboxypeptidase and bears strong sequence similarity to serine carboxypeptidases. Carboxypeptidases are a large class of proteases that act to cleave a single amino acid from the carboxy termini of proteins or peptides. The exact function of this protein, however, has not been determined. At least two alternatively spliced transcripts which encode the same protein have been observed. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9H3G5 |
| NCBI GenInfo Identifier: | 67476930 |
| NCBI Gene ID: | 54504 |
| NCBI Accession: | Q9H3G5.2 |
| UniProt Secondary Accession: | Q9H3G5,Q6UX20, Q8NBL7, Q96AR7, Q9HB41, A4D1A4, |
| UniProt Related Accession: | Q9H3G5 |
| Molecular Weight: | 476 |
| NCBI Full Name: | Probable serine carboxypeptidase CPVL |
| NCBI Synonym Full Names: | carboxypeptidase, vitellogenic-like |
| NCBI Official Symbol: | CPVL |
| NCBI Official Synonym Symbols: | HVLP |
| NCBI Protein Information: | probable serine carboxypeptidase CPVL; VCP-like protein; carboxypeptidase WUG; CP-Mac carboxypeptidase; vitellogenic carboxypeptidase-like protein |
| UniProt Protein Name: | Probable serine carboxypeptidase CPVL |
| UniProt Synonym Protein Names: | Carboxypeptidase, vitellogenic-like; Vitellogenic carboxypeptidase-like protein; VCP-like protein; hVLP |
| Protein Family: | Probable serine carboxypeptidase |
| UniProt Gene Name: | CPVL |
| UniProt Entry Name: | CPVL_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CPVL antibody (CAB12370) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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