Metabolism Antibodies 1
Anti-CPT1C Antibody (CAB13849)
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- SKU:
- CAB13849
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Description
| Antibody Name: | Anti-CPT1C Antibody |
| Antibody SKU: | CAB13849 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 270-400 of human CPT1C (NP_001129524.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse brain, Mouse testis, Mouse kidney, Rat brain, Rat testis, Rat kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 270-400 of human CPT1C (NP_001129524.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LYRH RLNR QEIP PTLL MGMR PLCS AQYE KIFN TTRI PGVQ KDYI RHLH DSQH VAVF HRGR FFRM GTHS RNSL LSPR ALEQ QFQR ILDD PSPA CPHE EHLA ALTA APRG TWAQ VRTS LKTQ AAEA LEAV EGA |
| Gene ID: | 126129 |
| Uniprot: | Q8TCG5 |
| Cellular Location: | Cell junction, Cell projection, Endoplasmic reticulum, Mitochondrion outer membrane, Multi-pass membrane protein, axon, dendrite, synapse |
| Calculated MW: | 81kDa/89kDa/90kDa |
| Observed MW: | 91kDa |
| Synonyms: | CPT1C, CATL1, CPT1-B, CPT1P, CPTI-B, CPTIC, SPG73 |
| Background: | This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein regulates the beta-oxidation and transport of long-chain fatty acids into mitochondria, and may play a role in the regulation of feeding behavior and whole-body energy homeostasis. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene. |
| UniProt Protein Function: | CPT1C: a member of the carnitine/choline acetyltransferase family. The encoded protein regulates the beta-oxidation and transport of long-chain fatty acids into mitochondria, and may play a role in the regulation of feeding behavior and whole-body energy homeostasis. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Transferase; Lipid Metabolism - fatty acid; EC 2.3.1.21 Chromosomal Location of Human Ortholog: 19q13.33 Cellular Component: axon; dendrite; endoplasmic reticulum Molecular Function:protein binding Disease: Spastic Paraplegia 73, Autosomal Dominant |
| NCBI Summary: | This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein regulates the beta-oxidation and transport of long-chain fatty acids into mitochondria, and may play a role in the regulation of feeding behavior and whole-body energy homeostasis. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] |
| UniProt Code: | Q8TCG5 |
| NCBI GenInfo Identifier: | 57013809 |
| NCBI Gene ID: | 126129 |
| NCBI Accession: | Q8TCG5.1 |
| UniProt Secondary Accession: | Q8TCG5,Q5K6N5, Q8N6Q9, Q8NDS6, Q8TE84, A8K0Z8, |
| UniProt Related Accession: | Q8TCG5 |
| Molecular Weight: | 81,000 Da |
| NCBI Full Name: | Carnitine O-palmitoyltransferase 1, brain isoform |
| NCBI Synonym Full Names: | carnitine palmitoyltransferase 1C |
| NCBI Official Symbol: | CPT1C |
| NCBI Official Synonym Symbols: | CATL1; CPT1P; CPTIC; SPG73; CPT1-B; CPTI-B |
| NCBI Protein Information: | carnitine O-palmitoyltransferase 1, brain isoform |
| UniProt Protein Name: | Carnitine O-palmitoyltransferase 1, brain isoform |
| UniProt Synonym Protein Names: | CPT IC; Carnitine O-palmitoyltransferase I, brain isoform; CPTI-B; Carnitine palmitoyltransferase 1C |
| Protein Family: | Carnitine O-palmitoyltransferase |
| UniProt Gene Name: | CPT1C |
| UniProt Entry Name: | CPT1C_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CPT1C antibody (CAB13849) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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