Cell Biology Antibodies 2

Anti-CPQ Antibody (CAB12062)

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SKU:
CAB12062
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-CPQ Antibody
Antibody SKU:CAB12062
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CPQ (NP_057218.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:293T, LO2, Mouse kidney, Rat kidney
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CPQ (NP_057218.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MKFL IFAF FGGV HLLS LCSG KAIC KNGI SKRT FEEI KEEI ASCG DVAK AIIN LAVY GKAQ NRSY ERLA LLVD TVGP RLSG SKNL EKAI QIMY QNLQ QDGL
Gene ID:10404
Uniprot:Q9Y646
Cellular Location:Endoplasmic reticulum, Golgi apparatus, Lysosome, Secreted
Calculated MW:51kDa
Observed MW:57-60kDa
Synonyms:CPQ, LDP, PGCP
Background:This gene encodes a metallopeptidase that belongs to the peptidase M28 family. The encoded protein may catalyze the cleavage of dipeptides with unsubstituted terminals into amino acids.
UniProt Protein Function:PGCP: Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes more efficiently the hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in thyroxin hormone liberation from its TG/thyroglobulin precursor. Belongs to the peptidase M28 family.
UniProt Protein Details:

Protein type:EC 3.4.17.-; Protease; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 8q22.1

Cellular Component: cytoplasm; endoplasmic reticulum; extracellular space; Golgi apparatus; lysosome

Molecular Function:protein homodimerization activity

Biological Process: peptide catabolic process; proteolysis; thyroid hormone generation; tissue regeneration

NCBI Summary:This gene encodes a metallopeptidase that belongs to the peptidase M28 family. The encoded protein may catalyze the cleavage of dipeptides with unsubstituted terminals into amino acids. [provided by RefSeq, Jul 2013]
UniProt Code:Q9Y646
NCBI GenInfo Identifier:74735298
NCBI Gene ID:10404
NCBI Accession:Q9Y646.1
UniProt Secondary Accession:Q9Y646,Q8NBZ1, Q9UNM8, Q9Y5X6, B2RD88,
UniProt Related Accession:Q9Y646
Molecular Weight:52kDa
NCBI Full Name:Carboxypeptidase Q
NCBI Synonym Full Names:carboxypeptidase Q
NCBI Official Symbol:CPQ  
NCBI Official Synonym Symbols:LDP; PGCP  
NCBI Protein Information:carboxypeptidase Q
UniProt Protein Name:Carboxypeptidase Q
UniProt Synonym Protein Names:Lysosomal dipeptidase; Plasma glutamate carboxypeptidase
Protein Family:Carboxypeptidase
UniProt Gene Name:CPQ  
Anti-CPQ Antibody (CAB12062)Western blot analysis of extracts of various cell lines, using CPQ antibody (CAB12062) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
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