Cell Biology Antibodies 4

Anti-CPLX3 Antibody (CAB13694)

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SKU:
CAB13694
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-CPLX3 Antibody
Antibody SKU:CAB13694
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 59-158 of human CPLX3 (NP_001025176.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:Mouse brain, Mouse eye, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 59-158 of human CPLX3 (NP_001025176.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:DAQF TQRK AERA TLRS HFRD KYRL PKNE TDES QIQM AGGD VELP RELA KMIE EDTE EEEE KASV LGQL ASLP GLNL GSLK DKAQ ATLG DLKQ SAEK CHVM
Gene ID:594855
Uniprot:Q8WVH0
Cellular Location:Cell junction, Lipid-anchor, Membrane, synapse
Calculated MW:17kDa
Observed MW:18kDa
Synonyms:CPLX3, CPX-III, CPXIII, Nbla11589
Background:
UniProt Protein Function:CPLX3: Positively regulates a late step in synaptic vesicle exocytosis. Belongs to the complexin/synaphin family.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 15q24.1

Cellular Component: plasma membrane; synapse; cell junction; cytosol

Molecular Function:syntaxin binding; neurotransmitter transporter activity

Biological Process: synaptic vesicle exocytosis; insulin secretion; regulation of neurotransmitter secretion

UniProt Code:Q8WVH0
NCBI GenInfo Identifier:74751549
NCBI Gene ID:594855
NCBI Accession:Q8WVH0.1
UniProt Secondary Accession:Q8WVH0,Q8TEM6, Q9H818, D3DW66,
UniProt Related Accession:Q8WVH0
Molecular Weight:17,557 Da
NCBI Full Name:Complexin-3
NCBI Synonym Full Names:complexin 3
NCBI Official Symbol:CPLX3  
NCBI Official Synonym Symbols:CPXIII; CPX-III; Nbla11589  
NCBI Protein Information:complexin-3; CPX III; complexin III
UniProt Protein Name:Complexin-3
UniProt Synonym Protein Names:Complexin III; CPX III
Protein Family:Complexin
UniProt Gene Name:CPLX3  
UniProt Entry Name:CPLX3_HUMAN
Anti-CPLX3 Antibody (CAB13694)Western blot analysis of extracts of various cell lines, using CPLX3 antibody (CAB13694) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
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