Cell Biology Antibodies 13
Anti-CPA4 Antibody (CAB17701)
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- SKU:
- CAB17701
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CPA4 Antibody |
| Antibody SKU: | CAB17701 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 114-280 of human CPA4 (NP_057436.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HepG2, A-549, 293T, Mouse stomach, Mouse brain, Rat testis, Rat lung, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 114-280 of human CPA4 (NP_057436.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | SSNN FNYG AYHS LEAI YHEM DNIA ADFP DLAR RVKI GHSF ENRP MYVL KFST GKGV RRPA VWLN AGIH SREW ISQA TAIW TARK IVSD YQRD PAIT SILE KMDI FLLP VANP DGYV YTQT QNRL WRKT RSRN PGSS CIGA DPNR NWNA SFAG KGAS DNPC SEVY HGP |
| Gene ID: | 51200 |
| Uniprot: | Q9UI42 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 47kDa |
 | Western blot - CPA4 Polyclonal Antibody (CAB17701) |
| Synonyms: | CPA3, CPA4 |
| Background: | This gene is a member of the carboxypeptidase A/B subfamily, and it is located in a cluster with three other family members on chromosome 7. Carboxypeptidases are zinc-containing exopeptidases that catalyze the release of carboxy-terminal amino acids, and are synthesized as zymogens that are activated by proteolytic cleavage. This gene could be involved in the histone hyperacetylation pathway. It is imprinted and may be a strong candidate gene for prostate cancer aggressiveness. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | CPA4: Metalloprotease that could be involved in the histone hyperacetylation pathway. Belongs to the peptidase M14 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; EC 3.4.17.-; Secreted; Protease Chromosomal Location of Human Ortholog: 7q32 Cellular Component: extracellular space Molecular Function:metallocarboxypeptidase activity |
| NCBI Summary: | This gene is a member of the carboxypeptidase A/B subfamily, and it is located in a cluster with three other family members on chromosome 7. Carboxypeptidases are zinc-containing exopeptidases that catalyze the release of carboxy-terminal amino acids, and are synthesized as zymogens that are activated by proteolytic cleavage. This gene could be involved in the histone hyperacetylation pathway. It is imprinted and may be a strong candidate gene for prostate cancer aggressiveness. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UI42 |
| NCBI GenInfo Identifier: | 61252703 |
| NCBI Gene ID: | 51200 |
| NCBI Accession: | Q9UI42.2 |
| UniProt Secondary Accession: | Q9UI42,Q86UY9, B7Z576, |
| UniProt Related Accession: | Q9UI42 |
| Molecular Weight: | 43,570 Da |
| NCBI Full Name: | Carboxypeptidase A4 |
| NCBI Synonym Full Names: | carboxypeptidase A4 |
| NCBI Official Symbol: | CPA4 |
| NCBI Official Synonym Symbols: | CPA3 |
| NCBI Protein Information: | carboxypeptidase A4 |
| UniProt Protein Name: | Carboxypeptidase A4 |
| UniProt Synonym Protein Names: | Carboxypeptidase A3 |
| Protein Family: | Carboxypeptidase |
| UniProt Gene Name: | CPA4 |
| UniProt Entry Name: | CBPA4_HUMAN |
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