Cell Biology Antibodies 4
Anti-CPA2 Antibody (CAB14373)
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- SKU:
- CAB14373
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CPA2 Antibody |
| Antibody SKU: | CAB14373 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 115-419 of human CPA2 (NP_001860.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-87MG, SH-SY5Y, Mouse pancreas, Rat pancreas |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 115-419 of human CPA2 (NP_001860.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | SGNF NFGA YHTL EEIS QEMD NLVA EHPG LVSK VNIG SSFE NRPM NVLK FSTG GDKP AIWL DAGI HARE WVTQ ATAL WTAN KIVS DYGK DPSI TSIL DALD IFLL PVTN PDGY VFSQ TKNR MWRK TRSK VSGS LCVG VDPN RNWD AGFG GPGA SSNP CSDS YHGP SANS EVEV KSIV DFIK SHGK VKAF ITLH SYSQ LLMF PYGY KCTK LDDF DELS EVAQ KAAQ SLRS LHGT KYKV GPIC SVIY QASG GSID WSYD YGIK YSFA FELR DTGR YGFL LPAR QILP TAEE TWLG LKAI MEHV RDHP Y |
| Gene ID: | 1358 |
| Uniprot: | P48052 |
| Cellular Location: | Secreted |
| Calculated MW: | 47kDa |
| Observed MW: | 47kDa |
| Synonyms: | CPA2 |
| Background: | Three different forms of human pancreatic procarboxypeptidase A have been isolated. The encoded protein represents the A2 form, which is a monomeric protein with different biochemical properties from the A1 and A3 forms. The A2 form of pancreatic procarboxypeptidase acts on aromatic C-terminal residues and is a secreted protein. |
| UniProt Protein Function: | CPA2: Three different forms of human pancreatic procarboxypeptidase A have been isolated. The encoded protein represents the A2 form, which is a monomeric protein with different biochemical properties from the A1 and A3 forms. The A2 form of pancreatic procarboxypeptidase acts on aromatic C-terminal residues and is a secreted protein. [provided by RefSeq, Dec 2008] |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; EC 3.4.17.15; Protease; Secreted Chromosomal Location of Human Ortholog: 7q32 Cellular Component: extracellular region Molecular Function:carboxypeptidase activity; zinc ion binding; metallocarboxypeptidase activity Biological Process: vacuolar protein catabolic process; proteolysis |
| NCBI Summary: | Three different forms of human pancreatic procarboxypeptidase A have been isolated. The encoded protein represents the A2 form, which is a monomeric protein with different biochemical properties from the A1 and A3 forms. The A2 form of pancreatic procarboxypeptidase acts on aromatic C-terminal residues and is a secreted protein. [provided by RefSeq, Dec 2008] |
| UniProt Code: | P48052 |
| NCBI GenInfo Identifier: | 294862522 |
| NCBI Gene ID: | 1358 |
| NCBI Accession: | P48052.3 |
| UniProt Secondary Accession: | P48052,Q53XS1, Q96A12, Q96QN3, Q9UCF1, A4D1M4, C9JIK1 |
| UniProt Related Accession: | P48052 |
| Molecular Weight: | 47,030 Da |
| NCBI Full Name: | Carboxypeptidase A2 |
| NCBI Synonym Full Names: | carboxypeptidase A2 (pancreatic) |
| NCBI Official Symbol: | CPA2 |
| NCBI Protein Information: | carboxypeptidase A2 |
| UniProt Protein Name: | Carboxypeptidase A2 |
| Protein Family: | Carboxypeptidase |
| UniProt Gene Name: | CPA2 |
| UniProt Entry Name: | CBPA2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CPA2 antibody (CAB14373) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
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