Cell Biology Antibodies 5

Anti-COX7A1 Antibody (CAB14721)

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SKU:
CAB14721
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-COX7A1 Antibody
Antibody SKU:CAB14721
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-79 of human COX7A1 (NP_001855.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-79 of human COX7A1 (NP_001855.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MQAL RVSQ ALIR SFSS TARN RFQN RVRE KQKL FQED NDIP LYLK GGIV DNIL YRVT MTLC LGGT VYSL YSLG WASF PRN
Gene ID:1346
Uniprot:P24310
Cellular Location:Mitochondrion inner membrane
Calculated MW:9kDa
Observed MW:Refer to figures
Synonyms:COX7A, COX7AH, COX7AM, COX7A1
Background:Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (muscle isoform) of subunit VIIa and the polypeptide 1 is present only in muscle tissues. Other polypeptides of subunit VIIa are present in both muscle and nonmuscle tissues, and are encoded by different genes.
UniProt Protein Function:COX7A1: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Belongs to the cytochrome c oxidase VIIa family.
UniProt Protein Details:

Protein type:Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.1

Cellular Component: mitochondrion

Biological Process: generation of precursor metabolites and energy

NCBI Summary:Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (muscle isoform) of subunit VIIa and the polypeptide 1 is present only in muscle tissues. Other polypeptides of subunit VIIa are present in both muscle and nonmuscle tissues, and are encoded by different genes. [provided by RefSeq, Jul 2008]
UniProt Code:P24310
NCBI GenInfo Identifier:399287
NCBI Gene ID:1346
NCBI Accession:P24310.2
UniProt Related Accession:P24310
Molecular Weight:9,118 Da
NCBI Full Name:Cytochrome c oxidase subunit 7A1, mitochondrial
NCBI Synonym Full Names:cytochrome c oxidase subunit 7A1
NCBI Official Symbol:COX7A1  
NCBI Official Synonym Symbols:COX7A; COX7AH; COX7AM  
NCBI Protein Information:cytochrome c oxidase subunit 7A1, mitochondrial
UniProt Protein Name:Cytochrome c oxidase subunit 7A1, mitochondrial
UniProt Synonym Protein Names:Cytochrome c oxidase subunit VIIa-heart; Cytochrome c oxidase subunit VIIa-H; Cytochrome c oxidase subunit VIIa-muscle; Cytochrome c oxidase subunit VIIa-M
Protein Family:Cytochrome c oxidase
UniProt Gene Name:COX7A1  
UniProt Entry Name:CX7A1_HUMAN
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