Cell Biology Antibodies 9
Anti-CORO1C Antibody (CAB4568)
- SKU:
- CAB4568
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CORO1C
- Synonyms:
- HCRNN4
- Research Area:
- Cell Biology
Description
| Product Name: | CORO1C Rabbit pAb |
| Product Code: | CAB4568 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | CORO1C, HCRNN4 |
| Applications: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 375-474 of human CORO1C (NP_055140.1). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | SW480 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 375-474 of human CORO1C (NP_055140.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | EEWF EGKN ADPI LISL KHGY IPGK NRDL KVVK KNIL DSKP TANK KCDL ISIP KKTT DTAS VQNE AKLD EILK EIKS IKDT ICNQ DERI SKLE QQMA KIAA |
| Gene ID: | 23603 |
| Uniprot: | Q9ULV4 |
| Cellular Location: | Cell membrane, Cell projection, Cytoplasm, cytoskeleton, lamellipodium |
| Calculated MW: | 53kDa/54kDa/58kDa |
| Observed MW: | 60kDa |
| UniProt Protein Function: | coronin 1C: an ubiquitous, actin-binding cytoskeletal protein. May be involved in cytokinesis and motility. Belongs to the WD-repeat coronin family. |
| UniProt Protein Details: | Protein type:Actin-binding; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 12q24.1 Cellular Component: focal adhesion; lamellipodium; cytoplasm; plasma membrane; actin cytoskeleton Molecular Function:actin filament binding Biological Process: signal transduction; actin cytoskeleton organization and biogenesis; phagocytosis |
| NCBI Summary: | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2013] |
| UniProt Code: | Q9ULV4 |
| NCBI GenInfo Identifier: | 12643898 |
| NCBI Gene ID: | 23603 |
| NCBI Accession: | Q9ULV4.1 |
| UniProt Secondary Accession: | Q9ULV4,Q9NSK5, A7MAP0, A7MAP1, B3KU12, |
| UniProt Related Accession: | Q9ULV4 |
| Molecular Weight: | 474 |
| NCBI Full Name: | Coronin-1C |
| NCBI Synonym Full Names: | coronin, actin binding protein, 1C |
| NCBI Official Symbol: | CORO1C |
| NCBI Official Synonym Symbols: | HCRNN4 |
| NCBI Protein Information: | coronin-1C; coronin-3; coronin 1C; coronin, actin-binding protein, 1C |
| UniProt Protein Name: | Coronin-1C |
| UniProt Synonym Protein Names: | Coronin-3; hCRNN4 |
| Protein Family: | Coronin |
| UniProt Gene Name: | CORO1C |
| UniProt Entry Name: | COR1C_HUMAN |