| UniProt Protein Function: | COL16A1: Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology. Belongs to the fibril-associated collagens with interrupted helices (FACIT) family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Motility/polarity/chemotaxis; Secreted; Extracellular matrix; Secreted, signal peptideChromosomal Location of Human Ortholog: 1p35-p34Cellular Component: proteinaceous extracellular matrix; endoplasmic reticulum lumen; extracellular region; collagen type XVIMolecular Function: integrin binding; protein bindingBiological Process: integrin-mediated signaling pathway; collagen catabolic process; extracellular matrix disassembly; extracellular matrix organization and biogenesis; female pregnancy; cell adhesion |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes the alpha chain of type XVI collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. High levels of type XVI collagen have been found in fibroblasts and keratinocytes, and in smooth muscle and amnion. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q07092 |
| NCBI GenInfo Identifier: | 143811380 |
| NCBI Gene ID: | 1307 |
| NCBI Accession: | Q07092.2 |
| UniProt Secondary Accession: | Q07092,Q16593, Q59F89, Q71RG9 |
| UniProt Related Accession: | Q07092 |
| Molecular Weight: | |
| NCBI Full Name: | Collagen alpha-1(XVI) chain |
| NCBI Synonym Full Names: | collagen, type XVI, alpha 1 |
| NCBI Official Symbol: | COL16A1 |
| NCBI Official Synonym Symbols: | 447AA; FP1572 |
| NCBI Protein Information: | collagen alpha-1(XVI) chain; collagen alpha-1(XVI) chain; alpha 1 type XVI collagen; collagen XVI, alpha-1 polypeptide |
| UniProt Protein Name: | Collagen alpha-1(XVI) chain |
| UniProt Synonym Protein Names: | |
| Protein Family: | Collagen |
| UniProt Gene Name: | COL16A1 |
| UniProt Entry Name: | COGA1_HUMAN |
