Cell Biology Antibodies 15

Anti-COG3 Antibody (CAB17785)

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SKU:
CAB17785
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-COG3 Antibody
Antibody SKU:CAB17785
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human COG3 (NP_113619.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:22Rv1, HeLa, Mouse brain, Mouse testis, Mouse lung, Rat testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human COG3 (NP_113619.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAEA ALLL LPEA AAER DARE KLAL WDRR PDTT APLT DRQT DSVL ELKA AAEN LPVP AELP IEDL CSLT SQSL PIEL TSVV PEST EDIL LKGF TSLG MEEE RIET AQQF FSWF AKLQ TQMD QDEG TKYR QMRD YLSG FQEQ CDAI LNDV NSAL QHLE SLQK QYLF VSNK TGTL HEAC EQLL KEQS ELVD LAEN IQQK LSYF NELE TINT KLNS PTLS VNSD GFIP MLAK LDDC ITYI SSHP NFKD YPIY LLKF KQCL SKAL HLMK TYTV NTLQ TLTS QLLK RDPS SVPN ADNA FTLF YVKF
Gene ID:83548
Uniprot:Q96JB2
Cellular Location:
Calculated MW:50kDa/94kDa
Observed MW:94kDa
Anti-COG3 Antibody (CAB17785)Western blot - COG3 Polyclonal Antibody (CAB17785)
Synonyms:COG3, SEC34
Background:This gene encodes a component of the conserved oligomeric Golgi (COG) complex which is composed of eight different subunits and is required for normal Golgi morphology and localization. Defects in the COG complex result in multiple deficiencies in protein glycosylation. The protein encoded by this gene is involved in ER-Golgi transport.[provided by RefSeq, Jun 2011]
UniProt Protein Function:COG3: Involved in ER-Golgi transport. Belongs to the COG3 family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Vesicle; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 13q14.13

Cellular Component: cytoplasm; Golgi apparatus; Golgi membrane; Golgi transport complex; nucleoplasm; plasma membrane; trans-Golgi network membrane

Molecular Function:protein binding; protein transporter activity

Biological Process: ER to Golgi vesicle-mediated transport; Golgi organization and biogenesis; intra-Golgi vesicle-mediated transport; protein amino acid glycosylation; protein localization in organelle; protein stabilization; retrograde transport, vesicle recycling within Golgi; retrograde vesicle-mediated transport, Golgi to ER

NCBI Summary:This gene encodes a component of the conserved oligomeric Golgi (COG) complex which is composed of eight different subunits and is required for normal Golgi morphology and localization. Defects in the COG complex result in multiple deficiencies in protein glycosylation. The protein encoded by this gene is involved in ER-Golgi transport.[provided by RefSeq, Jun 2011]
UniProt Code:Q96JB2
NCBI GenInfo Identifier:85701302
NCBI Gene ID:83548
NCBI Accession:Q96JB2.3
UniProt Secondary Accession:Q96JB2,Q5VT70, Q8IXX4, Q9BZ92, B2RAW5,
UniProt Related Accession:Q96JB2
Molecular Weight:50,540 Da
NCBI Full Name:Conserved oligomeric Golgi complex subunit 3
NCBI Synonym Full Names:component of oligomeric golgi complex 3
NCBI Official Symbol:COG3  
NCBI Official Synonym Symbols:SEC34  
NCBI Protein Information:conserved oligomeric Golgi complex subunit 3
UniProt Protein Name:Conserved oligomeric Golgi complex subunit 3
UniProt Synonym Protein Names:Component of oligomeric Golgi complex 3; Vesicle-docking protein SEC34 homolog; p94
Protein Family:Conserved oligomeric Golgi complex
UniProt Gene Name:COG3  
UniProt Entry Name:COG3_HUMAN
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