Cell Biology Antibodies 13
Anti-COBL Antibody (CAB17661)
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- SKU:
- CAB17661
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-COBL Antibody |
| Antibody SKU: | CAB17661 |
| Antibody Size: | 20uL, 50 uL |
| Application: | WB |
| Reactivity: | Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1100 to the C-terminus of human COBL (NP_001333371.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Rat |
| Positive Samples: |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1100 to the C-terminus of human COBL (NP_001333371.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | QRPV PKDT SLHS ALME AIHS AGGK DRLR KTAE HTGE GRPA KLSY TEAE GERS ALLA AIRG HSGT CSLR KALS APRT ASRF STGT LSNT ADAR QALM DAIR SGTG AARL RKVP LLV |
| Gene ID: | 23242 |
| Uniprot: | O75128 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | COBL |
| Background: | This gene encodes a protein that contains WH2 domains (WASP, Wiskott-Aldrich syndrome protein, homology domain-2) that interact with actin. The encoded actin regulator protein is required for growth and assembly of brush border microvilli that play a role in maintaining intestinal homeostasis. A similar protein in mouse functions in midbrain neural tube closure. A pseudogene of this gene is located on chromosome X. [provided by RefSeq, Oct 2016] |
| UniProt Protein Function: | cordon-bleu: 7 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell development/differentiation; Actin-binding Chromosomal Location of Human Ortholog: 7p12.1 Cellular Component: actin filament; axon; cell cortex; cell soma; dendrite; membrane; perinuclear region of cytoplasm; plasma membrane; ruffle Molecular Function:actin monomer binding Biological Process: actin filament network formation; actin filament polymerization; collateral sprouting in the absence of injury; embryonic axis specification; floor plate development; gut development; liver development; neural tube closure; notochord development; somite specification |
| UniProt Code: | O75128 |
| NCBI GenInfo Identifier: | 31581524 |
| NCBI Gene ID: | 23242 |
| NCBI Accession: | NP_056013.2 |
| UniProt Secondary Accession: | O75128,Q2T9J3, Q504Y4, Q86XA7, Q8N304, Q8TCM1, A4D257 A7E2B0, B7ZLW9, B9EGF8, |
| UniProt Related Accession: | O75128 |
| Molecular Weight: | 136,682 Da |
| NCBI Full Name: | protein cordon-bleu isoform b |
| NCBI Synonym Full Names: | cordon-bleu WH2 repeat protein |
| NCBI Official Symbol: | COBL |
| NCBI Protein Information: | protein cordon-bleu |
| UniProt Protein Name: | Protein cordon-bleu |
| Protein Family: | Protein cordon |
| UniProt Gene Name: | COBL |
| UniProt Entry Name: | COBL_HUMAN |
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