Cell Biology Antibodies 5

Anti-COA3 Antibody (CAB14585)

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SKU:
CAB14585
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-COA3 Antibody
Antibody SKU:CAB14585
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-106 of human COA3 (NP_001035521.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:MCF7
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-106 of human COA3 (NP_001035521.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MASS GAGD PLDS KRGE APFA QRID PTRE KLTP EQLH SMRQ AELA QWQK VLPR RRTR NIVT GLGI GALV LAIY GYTF YSIS QERF LDEL EDEA KAAR ARAL ARAS GS
Gene ID:28958
Uniprot:Q9Y2R0
Cellular Location:Mitochondrion inner membrane, Single-pass membrane protein
Calculated MW:11kDa
Observed MW:12kDa
Synonyms:COA3, CCDC56, COX25, HSPC009, MITRAC12
Background:This gene encodes a member of the cytochrome c oxidase assembly factor family. Studies of a related gene in fly suggest that the encoded protein is localized to mitochondria and is essential for cytochrome c oxidase function.
UniProt Protein Function:CCDC56: Putative COX assembly factor. Belongs to the COA3 family.
UniProt Protein Details:

Protein type:Membrane protein, integral; Mitochondrial

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: mitochondrion; integral to mitochondrial inner membrane

Molecular Function:protein binding

Biological Process: mitochondrial respiratory chain complex IV assembly

NCBI Summary:This gene encodes a member of the cytochrome c oxidase assembly factor family. Studies of a related gene in fly suggest that the encoded protein is localized to mitochondria and is essential for cytochrome c oxidase function. [provided by RefSeq, Nov 2012]
UniProt Code:Q9Y2R0
NCBI GenInfo Identifier:94536771
NCBI Gene ID:28958
NCBI Accession:NP_001035521.1
UniProt Secondary Accession:Q9Y2R0,A8K498,
UniProt Related Accession:Q9Y2R0
Molecular Weight:11,731 Da
NCBI Full Name:cytochrome c oxidase assembly factor 3 homolog, mitochondrial
NCBI Synonym Full Names:cytochrome c oxidase assembly factor 3
NCBI Official Symbol:COA3  
NCBI Official Synonym Symbols:CCDC56; HSPC009; MITRAC12  
NCBI Protein Information:cytochrome c oxidase assembly factor 3 homolog, mitochondrial
UniProt Protein Name:Cytochrome c oxidase assembly factor 3 homolog, mitochondrial
UniProt Synonym Protein Names:Coiled-coil domain-containing protein 56; Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 12 kDa
Protein Family:Cytochrome c oxidase assembly factor
UniProt Gene Name:COA3  
UniProt Entry Name:COA3_HUMAN
Anti-COA3 Antibody (CAB14585)Western blot analysis of extracts of MCF7 cells, using COA3 antibody (CAB14585) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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