Cell Cycle Antibodies 1

Anti-CNTRL Antibody (CAB15138)

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SKU:
CAB15138
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Cycle

Description

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Antibody Name:Anti-CNTRL Antibody
Antibody SKU:CAB15138
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 250-500 of human CNTRL (NP_008949.4).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:Raji, Mouse lung, Mouse spleen
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 250-500 of human CNTRL (NP_008949.4).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:LEGQ PVTT QDRQ EAFE RFSL EEVE RLER DLEK KMIE TEEL KSKQ TRFL EEIK NQDK LNKS LKEE AMLQ KQSC EELK SDLN TKNE LLKQ KTIE LTRA CQKQ YELE QELA FYKI DAKF EPLN YYPS EYAE IDKA PDES PYIG KSRY KRNM FATE SYII DSAQ AVQI KKME PDEQ LRND HMNL RGHT PLDT QLED KEKK ISAA QTRL SELH DEIE KAEQ QILR ATEE FKQL EEAI QLKK ISEA GKDL LYKQ LSG
Gene ID:11064
Uniprot:Q7Z7A1
Cellular Location:Cytoplasm, centrosome, cytoskeleton, microtubule organizing center
Calculated MW:56kDa/116kDa/205kDa/268kDa
Observed MW:280KDa
Synonyms:CNTRL, CEP1, CEP110, FAN, bA165P4.1
Background:This gene encodes a centrosomal protein required for the centrosome to function as a microtubule organizing center. The gene product is also associated with centrosome maturation. One version of stem cell myeloproliferative disorder is the result of a reciprocal translocation between chromosomes 8 and 9, with the breakpoint associated with fibroblast growth factor receptor 1 and centrosomal protein 1.
UniProt Protein Function:Involved in cell cycle progression and cytokinesis. During the late steps of cytokinesis, anchors exocyst and SNARE complexes at the midbody, thereby allowing secretory vesicle-mediated abscission.
NCBI Summary:This gene encodes a centrosomal protein required for the centrosome to function as a microtubule organizing center. The gene product is also associated with centrosome maturation. One version of stem cell myeloproliferative disorder is the result of a reciprocal translocation between chromosomes 8 and 9, with the breakpoint associated with fibroblast growth factor receptor 1 and centrosomal protein 1. [provided by RefSeq, Jul 2008]
UniProt Code:Q7Z7A1
NCBI GenInfo Identifier:1061899776
NCBI Gene ID:11064
NCBI Accession:NP_001317691.1
UniProt Secondary Accession:Q7Z7A1,Q3MN79, Q5FWF8, Q5JVD0, Q6MZR3, Q6PKC1, Q8TEP3 Q9Y489, A2A2Y1, B2RP67,
UniProt Related Accession:Q7Z7A1
Molecular Weight:Calculated: 56kDa; 116kDa; 205kDa; 268kDaObserved: 110kDa
NCBI Full Name:centriolin isoform 2
NCBI Synonym Full Names:centriolin
NCBI Official Symbol:CNTRL  
NCBI Official Synonym Symbols:FAN; CEP1; CEP110; bA165P4.1  
NCBI Protein Information:centriolin
UniProt Protein Name:Centriolin
UniProt Synonym Protein Names:Centrosomal protein 1; Centrosomal protein of 110 kDa; Cep110
Protein Family:Centriolin
UniProt Gene Name:CNTRL  
Anti-CNTRL Antibody (CAB15138)Western blot analysis of extracts of various cell lines, using CNTRL antibody (CAB15138) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s.
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