Cell Biology Antibodies 3

Anti-CNTN5 Antibody (CAB12654)

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SKU:
CAB12654
Product Type:
Antibody
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-CNTN5 Antibody
Antibody SKU:CAB12654
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 19-220 of human CNTN5 (NP_001230200.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 19-220 of human CNTN5 (NP_001230200.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:EYSK SLPG LSTS YAAL LRIK KSSS SSLF GSKT RPRY SSPS LGTL SASS PSWL GAAQ NYYS PINL YHSS DAFK QDES VDYG PVFV QEPD DIIF PTDS DEKK VALN CEVR GNPV PSYR WLRN GTEI DLES DYRY SLID GTFI ISNP SEAK DSGH YQCL ATNT VGSI LSRE ATLQ FAYL GNFS GRTR SAVS VREG QGVV LMCS PP
Gene ID:53942
Uniprot:O94779
Cellular Location:Cell membrane, GPI-anchor, Lipid-anchor
Calculated MW:100kDa/112kDa/120kDa
Observed MW:Refer to Figures
Synonyms:CNTN5, HNB-2s, NB-2
Background:The protein encoded by this gene is a member of the immunoglobulin superfamily, and contactin family, which mediate cell surface interactions during nervous system development. This protein is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
UniProt Protein Function:CNTN5: Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system. Belongs to the immunoglobulin superfamily. Contactin family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Cell adhesion; Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 11q22.1

Cellular Component: cytosol; extracellular region; plasma membrane

Biological Process: C-terminal protein lipidation

NCBI Summary:The protein encoded by this gene is a member of the immunoglobulin superfamily, and contactin family, which mediate cell surface interactions during nervous system development. This protein is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
UniProt Code:O94779
NCBI GenInfo Identifier:55976223
NCBI Gene ID:53942
NCBI Accession:O94779.2
UniProt Secondary Accession:O94779,O94780, Q49AF3, A1L4P0, B7ZM07, E9PKE8,
UniProt Related Accession:O94779
Molecular Weight:121kDa
NCBI Full Name:Contactin-5
NCBI Synonym Full Names:contactin 5
NCBI Official Symbol:CNTN5  
NCBI Official Synonym Symbols:NB-2; HNB-2s  
NCBI Protein Information:contactin-5
UniProt Protein Name:Contactin-5
UniProt Synonym Protein Names:Neural recognition molecule NB-2; hNB-2
Protein Family:Contactin
UniProt Gene Name:CNTN5  
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