Immunology Antibodies 2
Anti-CNPY3 Antibody (CAB7176)
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- SKU:
- CAB7176
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
| Antibody Name: | Anti-CNPY3 Antibody |
| Antibody SKU: | CAB7176 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 31-278 of human CNPY3 (NP_006577.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HepG2, MCF7, THP-1, HL-60, U-937 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 31-278 of human CNPY3 (NP_006577.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | GPSQ AGAE ENDW VRLP SKCE VCKY VAVE LKSA FEET GKTK EVIG TGYG ILDQ KASG VKYT KSDL RLIE VTET ICKR LLDY SLHK ERTG SNRF AKGM SETF ETLH NLVH KGVK VVMD IPYE LWNE TSAE VADL KKQC DVLV EEFE EVIE DWYR NHQE EDLT EFLC ANHV LKGK DTSC LAEQ WSGK KGDT AALG GKKS KKKS SRAK AAGG RSSS SKQR KELG GLEG DPSP EEDE GIQK ASPL THSP PDEL |
| Gene ID: | 10695 |
| Uniprot: | Q9BT09 |
| Cellular Location: | Endoplasmic reticulum |
| Calculated MW: | 5kDa/30kDa |
| Observed MW: | 38kDa |
| Synonyms: | CNPY3, CAG4A, ERDA5, PRAT4A, TNRC5 |
| Background: | This gene encodes a protein that binds members of the toll-like receptor protein family and functions as a chaperone to aid in folding and export of these proteins. Alternative splicing results in multiple transcript variants. Naturally occuring readthrough transcription occurs between this locus and the downstream GNMT (glycine N-methyltransferase) gene and is represented with GeneID:107080644. |
| UniProt Protein Function: | TNRC5: Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptative immune responses. Belongs to the canopy family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 6p21.1 Cellular Component: endoplasmic reticulum lumen Molecular Function:receptor binding Biological Process: toll-like receptor signaling pathway; innate immune response |
| NCBI Summary: | This gene encodes a protein that binds members of the toll-like receptor protein family and functions as a chaperone to aid in folding and export of these proteins. Alternative splicing results in multiple transcript variants. Naturally occuring readthrough transcription occurs between this locus and the downstream GNMT (glycine N-methyltransferase) gene and is represented with GeneID:107080644. [provided by RefSeq, Jan 2016] |
| UniProt Code: | Q9BT09 |
| NCBI GenInfo Identifier: | 74752319 |
| NCBI Gene ID: | 10695 |
| NCBI Accession: | Q9BT09.1 |
| UniProt Related Accession: | Q9BT09 |
| Molecular Weight: | |
| NCBI Full Name: | Protein canopy homolog 3 |
| NCBI Synonym Full Names: | canopy FGF signaling regulator 3 |
| NCBI Official Symbol: | CNPY3 |
| NCBI Official Synonym Symbols: | CAG4A; ERDA5; TNRC5; EIEE60; PRAT4A |
| NCBI Protein Information: | protein canopy homolog 3 |
| UniProt Protein Name: | Protein canopy homolog 3 |
| UniProt Synonym Protein Names: | CTG repeat protein 4a; Expanded repeat-domain protein CAG/CTG 5; Protein associated with TLR4; Trinucleotide repeat-containing gene 5 protein |
| Protein Family: | Protein canopy |
| UniProt Gene Name: | CNPY3 |
| UniProt Entry Name: | CNPY3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CNPY3 antibody (CAB7176) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 15s. |
 | Immunohistochemistry of paraffin-embedded mouse kidney using CNPY3 antibody (CAB7176) at dilution of 1:100 (40x lens). |
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