Description
Product Name: | CNN3 Rabbit pAb |
Product Code: | CAB20352 |
Size: | 50uL, 100uL |
Applications: | WB, IF |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant protein of human CNN3. |
Applications: | WB, IF |
Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | 293T, Mouse lung, Mouse testis, Mouse brain, Rat lung |
Immunogen: | Recombinant protein of human CNN3. |
Purification Method: | Affinity purification |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 1266 |
Uniprot: | Q15417 |
Calculated MW: | 36kDa |
Observed MW: | 37KDa |
UniProt Protein Function: | calponin 3: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. Belongs to the calponin family. Protein type: Motility/polarity/chemotaxis; Cytoskeletal Chromosomal Location of Human Ortholog: 1p22-p21 Cellular Component: actin cytoskeleton; cytoplasm; focal adhesion Biological Process: epithelial cell differentiation |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a protein with a markedly acidic C terminus; the basic N-terminus is highly homologous to the N-terminus of a related gene, CNN1. Members of the CNN gene family all contain similar tandemly repeated motifs. This encoded protein is associated with the cytoskeleton but is not involved in contraction. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q15417 |
NCBI GenInfo Identifier: | 6225157 |
NCBI Gene ID: | 1266 |
NCBI Accession: | Q15417.1 |
UniProt Secondary Accession: | Q15417,Q6FHA7, B4DFK6, B4DP09, F8WA86 |
UniProt Related Accession: | Q15417 |
Molecular Weight: | 31,380 Da |
NCBI Full Name: | Calponin-3 |
NCBI Synonym Full Names: | calponin 3 |
NCBI Official Symbol: | CNN3 |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | calponin-3 |
UniProt Protein Name: | Calponin-3 |
UniProt Synonym Protein Names: | Calponin, acidic isoform |
Protein Family: | Calponin |
UniProt Gene Name: | CNN3 |
UniProt Entry Name: | CNN3_HUMAN |