Cell Biology Antibodies 7
Anti-CNN1 Antibody (CAB16638)
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- SKU:
- CAB16638
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CNN1 Antibody |
| Antibody SKU: | CAB16638 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 130-180 of human CNN1 (NP_001290.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-87MG, PC-3, HeLa, Mouse spleen, Rat testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 130-180 of human CNN1 (NP_001290.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAKT KGNK VNVG VKYA EKQE RKFE PGKL REGR NIIG LQMG TNKF ASQQ GMT |
| Gene ID: | 1264 |
| Uniprot: | P51911 |
| Cellular Location: | |
| Calculated MW: | 31kDa/33kDa |
| Observed MW: | 33kDa |
| Synonyms: | CNN1, HEL-S-14, SMCC, Sm-Calp |
| Background: |
| UniProt Protein Function: | calponin 1: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. Belongs to the calponin family. |
| UniProt Protein Details: | Protein type:Contractile; Motility/polarity/chemotaxis; Actin-binding; Myosin-binding Chromosomal Location of Human Ortholog: 19p13.2-p13.1 Cellular Component: cytoskeleton; focal adhesion Molecular Function:calmodulin binding; actin binding Biological Process: regulation of smooth muscle contraction; actomyosin structure organization and biogenesis |
| UniProt Code: | P51911 |
| NCBI GenInfo Identifier: | 2829431 |
| NCBI Gene ID: | 1264 |
| NCBI Accession: | P51911.2 |
| UniProt Secondary Accession: | P51911,O00638, Q15416, Q8IY93, Q99438, B2R868, |
| UniProt Related Accession: | P51911 |
| Molecular Weight: | 33,170 Da |
| NCBI Full Name: | Calponin-1 |
| NCBI Synonym Full Names: | calponin 1, basic, smooth muscle |
| NCBI Official Symbol: | CNN1 |
| NCBI Official Synonym Symbols: | SMCC; Sm-Calp; HEL-S-14 |
| NCBI Protein Information: | calponin-1; basic calponin; calponins, basic; calponin H1, smooth muscle; epididymis secretory protein Li 14 |
| UniProt Protein Name: | Calponin-1 |
| UniProt Synonym Protein Names: | Basic calponin; Calponin H1, smooth muscle |
| Protein Family: | Calponin |
| UniProt Gene Name: | CNN1 |
| UniProt Entry Name: | CNN1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CNN1 antibody (CAB16638) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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