Cell Biology Antibodies 11
Anti-CNDP1 Antibody (CAB7485)
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- SKU:
- CAB7485
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CNDP1 Antibody |
| Antibody SKU: | CAB7485 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human CNDP1 (NP_116038.4). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, A-431, HepG2, Mouse kidney, Mouse brain, Rat spinal cord, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human CNDP1 (NP_116038.4). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MDPK LGRM AASL LAVL LLLL ERGM FSSP SPPP ALLE KVFQ YIDL HQDE FVQT LKEW VAIE SDSV QPVP RFRQ ELFR MMAV AADT LQRL GARV ASVD MGPQ QLPD GQSL PIPP VILA ELGS DPTK GTVC FYGH LDVQ PADR GDGW LTDP YVLT EVDG KLYG RGAT DNKG PVLA WINA VSAF RALE QDLP VNIK FIIE GMEE AGSV ALEE LVEK EKDR FFSG VDYI VISD NLWI SQRK PAIT YGTR GNSY FMVE VKCR DQDF HSGT FGGI LHEP MADL VALL |
| Gene ID: | 84735 |
| Uniprot: | Q96KN2 |
| Cellular Location: | Secreted |
| Calculated MW: | 56kDa |
| Observed MW: | 57kDa |
| Synonyms: | CNDP1, CN1, CPGL2, HsT2308 |
| Background: | This gene encodes a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This gene contains trinucleotide (CTG) repeat length polymorphism in the coding region. |
| UniProt Protein Function: | CNDP1: a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This gene contains trinucleotide (CTG) repeat length polymorphism in the coding region. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Amino Acid Metabolism - histidine; Protease; Secreted, signal peptide; Secreted; Other Amino Acids Metabolism - beta-alanine; EC 3.4.13.20 Chromosomal Location of Human Ortholog: 18q22.3 Cellular Component: extracellular region Molecular Function:dipeptidase activity; metallopeptidase activity; carboxypeptidase activity; metal ion binding Biological Process: proteolysis |
| UniProt Code: | Q96KN2 |
| NCBI GenInfo Identifier: | 21071039 |
| NCBI Gene ID: | 84735 |
| NCBI Accession: | NP_116038.4 |
| UniProt Secondary Accession: | Q96KN2,Q14D40, Q17S05, Q2TBG0, Q6UWK2, Q9BT98, |
| UniProt Related Accession: | Q96KN2 |
| Molecular Weight: | 56,706 Da |
| NCBI Full Name: | beta-Ala-His dipeptidase |
| NCBI Synonym Full Names: | carnosine dipeptidase 1 (metallopeptidase M20 family) |
| NCBI Official Symbol: | CNDP1 |
| NCBI Official Synonym Symbols: | CN1; CPGL2; HsT2308 |
| NCBI Protein Information: | beta-Ala-His dipeptidase |
| UniProt Protein Name: | Beta-Ala-His dipeptidase |
| UniProt Synonym Protein Names: | CNDP dipeptidase 1; Carnosine dipeptidase 1; Glutamate carboxypeptidase-like protein 2; Serum carnosinase |
| Protein Family: | Beta-Ala-His dipeptidase |
| UniProt Gene Name: | CNDP1 |
| UniProt Entry Name: | CNDP1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CNDP1 antibody (CAB7485) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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