KO Validated Antibodies 2

Anti-CLUH Antibody (CAB19979)[KO Validated]

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SKU:
CAB19979
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-CLUH Antibody [KO Validated]
Antibody SKU:CAB19979
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant protein of human CLUH.
Application:WB IHC IF
Recommended Dilution:WB 1:1000 - 1:4000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse
Positive Samples:293T
Immunogen:Recombinant protein of human CLUH.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:23277
Uniprot:O75153
Cellular Location:Cytoplasm, Cytoplasmic granule
Calculated MW:146kDa
Observed MW:160KDa
Anti-CLUH Antibody [KO Validated] (CAB19979)Western blot analysis of extracts from normal (control) and CLUH knockout (KO) 293T cells, using CLUH antibody (CAB19979) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
Synonyms:CLUH, CLU1, KIAA0664
Background:
UniProt Protein Function:eIF3-X: Involved in proper cytoplasmic distribution of mitochondria. Belongs to the CLU family.
UniProt Protein Details:

Protein type:Translation

Chromosomal Location of Human Ortholog: 17p13.3

Cellular Component: cytoplasm

Molecular Function:mRNA binding

Biological Process: intracellular distribution of mitochondria; mitochondrion organization and biogenesis

UniProt Code:O75153
NCBI GenInfo Identifier:87162455
NCBI Gene ID:23277
NCBI Accession:NP_056044.3
UniProt Secondary Accession:O75153,Q6AHY2, Q6P3X7, Q6ZUG8, Q8N4U7, Q9BTA3, Q9H979
UniProt Related Accession:O75153
Molecular Weight:Calculated: 146kDaObserved: 180kDa
NCBI Full Name:clustered mitochondria protein homolog
NCBI Synonym Full Names:clustered mitochondria (cluA/CLU1) homolog
NCBI Official Symbol:CLUH  
NCBI Official Synonym Symbols:CLU1; KIAA0664  
NCBI Protein Information:clustered mitochondria protein homolog
UniProt Protein Name:Clustered mitochondria protein homolog
Protein Family:Clustered mitochondria protein
UniProt Gene Name:CLUH  
UniProt Entry Name:CLU_HUMAN
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