Immunology Antibodies 2
Anti-CLEC5A Antibody (CAB2873)
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- SKU:
- CAB2873
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Description
| Antibody Name: | Anti-CLEC5A Antibody |
| Antibody SKU: | CAB2873 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-188 of human CLEC5A (NP_037384.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:1000 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | LO2, B cells, Mouse spleen, Rat spleen |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-188 of human CLEC5A (NP_037384.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | QIFN KSND GFTT TRSY GTVS QIFG SSSP SPNG FITT RSYG TVCP KDWE FYQA RCFF LSTS ESSW NESR DFCK GKGS TLAI VNTP EKLK FLQD ITDA EKYF IGLI YHRE EKRW RWIN NSVF NGNV TNQN QNFN CATI GLTK TFDA ASCD ISYR RICE KNAK |
| Gene ID: | 23601 |
| Uniprot: | Q9NY25 |
| Cellular Location: | Cell membrane, Single-pass type II membrane protein |
| Calculated MW: | 21kDa |
| Observed MW: | 20kDa |
| Synonyms: | CLEC5A, CLECSF5, MDL-1, MDL1 |
| Background: | This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein interacts with dnax-activation protein 12 and may play a role in cell activation. Alternative splice variants have been described but their full-length sequence has not been determined. |
| UniProt Code: | Q9NY25 |
| NCBI GenInfo Identifier: | 59797971 |
| NCBI Gene ID: | 23601 |
| NCBI Accession: | Q9NY25.1 |
| UniProt Secondary Accession: | Q9NY25,Q9R007, |
| UniProt Related Accession: | Q9NY25 |
| Molecular Weight: | 188 |
| NCBI Full Name: | C-type lectin domain family 5 member A |
| NCBI Synonym Full Names: | C-type lectin domain family 5, member A |
| NCBI Official Symbol: | CLEC5A |
| NCBI Official Synonym Symbols: | MDL1; MDL-1; CLECSF5 |
| NCBI Protein Information: | C-type lectin domain family 5 member A; C-type lectin superfamily member 5; myeloid DAP12-associating lectin 1; myeloid DAP12-associating lectin-1; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5 |
| UniProt Protein Name: | C-type lectin domain family 5 member A |
| UniProt Synonym Protein Names: | C-type lectin superfamily member 5; Myeloid DAP12-associating lectin 1; MDL-1 |
| UniProt Gene Name: | CLEC5A |
| UniProt Entry Name: | CLC5A_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CLEC5A antibody (CAB2873) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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