Immunology Antibodies 2

Anti-CLEC4D Antibody (CAB2697)

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SKU:
CAB2697
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology

Description

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Antibody Name:Anti-CLEC4D Antibody
Antibody SKU:CAB2697
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 39-215 of human CLEC4D (NP_525126.2).
Application:WB IF
Recommended Dilution:WB 1:1000 - 1:4000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse spleen, Rat lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 39-215 of human CLEC4D (NP_525126.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:CLVT HHNF SRCK RGTG VHKL EHHA KLKC IKEK SELK SAEG STWN CCPI DWRA FQSN CYFP LTDN KTWA ESER NCSG MGAH LMTI STEA EQNF IIQF LDRR LSYF LGLR DENA KGQW RWVD QTPF NPRR VFWH KNEP DNSQ GENC VVLV YNQD KWAW NDVP CNFE ASRI CKIP GTTL N
Gene ID:338339
Uniprot:Q8WXI8
Cellular Location:Membrane, Single-pass type II membrane protein
Calculated MW:24kDa
Observed MW:27KDa
Synonyms:CLEC4D, CD368, CLEC-6, CLEC6, CLECSF8, MCL, MPCL
Background:This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
UniProt Protein Function:CLEC4D: Functions as an endocytic receptor. May be involved in antigen uptake at the site of infection, either for clearance of the antigen, or for processing and further presentation to T cells.
UniProt Protein Details:

Protein type:Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13.31

Cellular Component: integral to membrane

Molecular Function:carbohydrate binding

Biological Process: innate immune response

UniProt Code:Q8WXI8
NCBI GenInfo Identifier:73916933
NCBI Gene ID:
NCBI Accession:Q8WXI8.2
Molecular Weight:
NCBI Full Name:C-type lectin domain family 4 member D
UniProt Protein Name:C-type lectin domain family 4 member D
UniProt Synonym Protein Names:C-type lectin superfamily member 8; C-type lectin-like receptor 6; CLEC-6
UniProt Gene Name:CLEC4D  
UniProt Entry Name:CLC4D_HUMAN
Anti-CLEC4D Antibody (CAB2697)Western blot analysis of extracts of various cell lines, using CLEC4D Rabbit pAb (CAB2697) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
Anti-CLEC4D Antibody (CAB2697)Immunofluorescence analysis of mouse spleen using CLEC4D Rabbit pAb (CAB2697) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
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