Cell Biology Antibodies 10
Anti-CLDN2 Antibody (CAB6560)
(No reviews yet)
Write a Review
- SKU:
- CAB6560
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CLDN2 Antibody |
| Antibody SKU: | CAB6560 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | IF |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-230 of human CLDN2 (NP_001164566.1). |
| Application: | IF |
| Recommended Dilution: | IF 1:50 - 1:100 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-230 of human CLDN2 (NP_001164566.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | WKTS SYVG ASIV TAVG FSKG LWME CATH STGI TQCD IYST LLGL PADI QAAQ AMMV TSSA ISSL ACII SVVG MRCT VFCQ ESRA KDRV AVAG GVFF ILGG LLGF IPVA WNLH GILR DFYS PLVP DSMK FEIG EALY LGII SSLF SLIA GIIL CFSC SSQR NRSN YYDA YQAQ PLAT RSSP RPGQ PPKV KSEF NSYS LTGY V |
| Gene ID: | 9075 |
| Uniprot: | P57739 |
| Cellular Location: | Cell junction, Cell membrane, Multi-pass membrane protein, tight junction |
| Calculated MW: | 24kDa |
| Observed MW: |
| Synonyms: | CLDN2, claudin-2 |
| Background: | This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene. |
| UniProt Protein Function: | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. |
| NCBI Summary: | This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010] |
| UniProt Code: | P57739 |
| NCBI GenInfo Identifier: | 12229749 |
| NCBI Gene ID: | 9075 |
| NCBI Accession: | P57739.1 |
| UniProt Secondary Accession: | P57739,B2R6B9, |
| UniProt Related Accession: | P57739 |
| Molecular Weight: | 25kDa |
| NCBI Full Name: | Claudin-2 |
| NCBI Synonym Full Names: | claudin 2 |
| NCBI Official Symbol: | CLDN2 |
| NCBI Protein Information: | claudin-2 |
| UniProt Protein Name: | Claudin-2 |
| UniProt Synonym Protein Names: | SP82 |
| Protein Family: | Claudin |
| UniProt Gene Name: | CLDN2 |
 | Immunofluorescence analysis of HeLa cells using CLDN2 antibody (CAB6560). Blue: DAPI for nuclear staining. |
View AllClose
Related Products
Human CLDN2 / Claudin-2 ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक