Cell Biology Antibodies 1

Anti-CISD1 Antibody (CAB10317)

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SKU:
CAB10317
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-CISD1 Antibody
Antibody SKU:CAB10317
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 29-108 of human CISD1 (NP_060934.1).
Application:WB IHC
Recommended Dilution:WB 1:1000 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa, Mouse liver, Mouse heart, Mouse skeletal muscle, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 29-108 of human CISD1 (NP_060934.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:LAYK RFYV KDHR NKAM INLH IQKD NPKI VHAF DMED LGDK AVYC RCWR SKKF PFCD GAHT KHNE ETGD NVGP LIIK KKET
Gene ID:55847
Uniprot:Q9NZ45
Cellular Location:Mitochondrion outer membrane, Single-pass type III membrane protein
Calculated MW:12kDa
Observed MW:12kDa
Synonyms:CISD1, C10orf70, MDS029, ZCD1, mitoNEET
Background:This gene encodes a protein with a CDGSH iron-sulfur domain and has been shown to bind a redox-active [2Fe-2S] cluster. The encoded protein has been localized to the outer membrane of mitochondria and is thought to play a role in regulation of oxidation. Genes encoding similar proteins are located on chromosomes 4 and 17, and a pseudogene of this gene is located on chromosome 2.
UniProt Protein Function:ZCD1: Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation. May be involved in Fe-S cluster shuttling and/or in redox reactions. Belongs to the CISD protein family.
UniProt Protein Details:

Protein type:Membrane protein, integral; Mitochondrial

Chromosomal Location of Human Ortholog: 10q21.1

Cellular Component: mitochondrion

NCBI Summary:This gene encodes a protein with a CDGSH iron-sulfur domain and has been shown to bind a redox-active [2Fe-2S] cluster. The encoded protein has been localized to the outer membrane of mitochondria and is thought to play a role in regulation of oxidation. Genes encoding similar proteins are located on chromosomes 4 and 17, and a pseudogene of this gene is located on chromosome 2. [provided by RefSeq, Feb 2012]
UniProt Code:Q9NZ45
NCBI GenInfo Identifier:25453105
NCBI Gene ID:55847
NCBI Accession:Q9NZ45.1
UniProt Secondary Accession:Q9NZ45,Q1X902,
UniProt Related Accession:Q9NZ45
Molecular Weight:12kDa
NCBI Full Name:CDGSH iron-sulfur domain-containing protein 1
NCBI Synonym Full Names:CDGSH iron sulfur domain 1
NCBI Official Symbol:CISD1  
NCBI Official Synonym Symbols:ZCD1; MDS029; C10orf70; mitoNEET  
NCBI Protein Information:CDGSH iron-sulfur domain-containing protein 1
UniProt Protein Name:CDGSH iron-sulfur domain-containing protein 1
UniProt Synonym Protein Names:MitoNEET
Protein Family:CDGSH iron-sulfur domain-containing protein
UniProt Gene Name:CISD1  
Anti-CISD1 Antibody (CAB10317)Western blot analysis of extracts of various cell lines, using CISD1 antibody (CAB10317) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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