Anti-CIRBP Antibody (CAB19290)
- SKU:
- CAB19290
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CIRBP
- Synonyms:
- CIRP
- Synonyms:
- cold-inducible RNA-binding protein
- Research Area:
- Metabolism
Description
| Product Name: | CIRBP Rabbit mAb |
| Product Code: | CAB19290 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | CIRBP, CIRP, cold-inducible RNA-binding protein |
| Applications: | WB, IHC, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human CIRBP. |
| Applications: | WB, IHC, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, HepG2, SH-SY5Y |
| Immunogen: | Recombinant protein of human CIRBP. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 1153 |
| Uniprot: | Q14011 |
| Cellular Location: | Cytoplasm, Nucleus, nucleoplasm |
| Calculated MW: | 19kDa |
| Observed MW: | 18KDa |
| UniProt Protein Function: | Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor. Promotes assembly of stress granules (SGs), when overexpressed. |
| UniProt Code: | Q14011 |
| NCBI GenInfo Identifier: | 5921786 |
| NCBI Gene ID: | 1153 |
| NCBI Accession: | Q14011.1 |
| UniProt Secondary Accession: | Q14011,B3KT17, B4E2X2, |
| UniProt Related Accession: | Q14011 |
| Molecular Weight: | 19kDa |
| NCBI Full Name: | Cold-inducible RNA-binding protein |
| NCBI Synonym Full Names: | cold inducible RNA binding protein |
| NCBI Official Symbol: | CIRBP |
| NCBI Official Synonym Symbols: | CIRP |
| NCBI Protein Information: | cold-inducible RNA-binding protein |
| UniProt Protein Name: | Cold-inducible RNA-binding protein |
| UniProt Synonym Protein Names: | A18 hnRNP; Glycine-rich RNA-binding protein CIRP |
| Protein Family: | Cold-inducible RNA-binding protein |
| UniProt Gene Name: | CIRBP |
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