Cell Biology Antibodies 13
Anti-CHST12 Antibody (CAB17721)
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- SKU:
- CAB17721
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CHST12 Antibody |
| Antibody SKU: | CAB17721 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 193-414 of human CHST12 (NP_061111.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse heart |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 193-414 of human CHST12 (NP_061111.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | GAPY RDPL RIPR EHVH NASA HLTF NKFW RRYG KLSR HLMK VKLK KYTK FLFV RDPF VRLI SAFR SKFE LENE EFYR KFAV PMLR LYAN HTSL PASA REAF RAGL KVSF ANFI QYLL DPHT EKLA PFNE HWRQ VYRL CHPC QIDY DFVG KLET LDED AAQL LQLL QVDR QLRF PPSY RNRT ASSW EEDW FAKI PLAW RQQL YKLY EADF VLFG YPKP ENLL RD |
| Gene ID: | 55501 |
| Uniprot: | Q9NRB3 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 48kDa |
 | Western blot - CHST12 Polyclonal Antibody (CAB17721) |
| Synonyms: | C4S-2, C4ST-2, C4ST2, CHST12 |
| Background: | The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. Alternatively spliced transcript variants differing only in their 5' UTRs have been found for this gene. [provided by RefSeq, Aug 2011] |
| UniProt Protein Function: | CHST12: Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Activity toward partially desulfated dermatan sulfate is however lower. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor. Belongs to the sulfotransferase 2 family. |
| UniProt Protein Details: | Protein type:Glycan Metabolism - chondroitin sulfate biosynthesis; Energy Metabolism - sulfur; Membrane protein, integral; EC 2.8.2.5; Transferase Chromosomal Location of Human Ortholog: 7p22 Cellular Component: Golgi membrane; membrane Molecular Function:chondroitin 4-sulfotransferase activity Biological Process: chondroitin sulfate biosynthetic process; dermatan sulfate biosynthetic process |
| NCBI Summary: | The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. Alternatively spliced transcript variants differing only in their 5' UTRs have been found for this gene. [provided by RefSeq, Aug 2011] |
| UniProt Code: | Q9NRB3 |
| NCBI GenInfo Identifier: | 61212140 |
| NCBI Gene ID: | 55501 |
| NCBI Accession: | Q9NRB3.2 |
| UniProt Secondary Accession: | Q9NRB3,Q502W3, Q9NXY7, A4D1Z9, |
| UniProt Related Accession: | Q9NRB3 |
| Molecular Weight: | 48,414 Da |
| NCBI Full Name: | Carbohydrate sulfotransferase 12 |
| NCBI Synonym Full Names: | carbohydrate (chondroitin 4) sulfotransferase 12 |
| NCBI Official Symbol: | CHST12 |
| NCBI Official Synonym Symbols: | C4S-2; C4ST2; C4ST-2 |
| NCBI Protein Information: | carbohydrate sulfotransferase 12 |
| UniProt Protein Name: | Carbohydrate sulfotransferase 12 |
| UniProt Synonym Protein Names: | Chondroitin 4-O-sulfotransferase 2; Chondroitin 4-sulfotransferase 2; C4ST-2; C4ST2; Sulfotransferase Hlo |
| Protein Family: | Carbohydrate sulfotransferase |
| UniProt Gene Name: | CHST12 |
| UniProt Entry Name: | CHSTC_HUMAN |
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