Metabolism Antibodies 1
Anti-CHST11 Antibody (CAB13734)
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- SKU:
- CAB13734
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Description
| Antibody Name: | Anti-CHST11 Antibody |
| Antibody SKU: | CAB13734 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 38-352 of human CHST11 (NP_060883.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Rat |
| Positive Samples: | Raji, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 38-352 of human CHST11 (NP_060883.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | HPVM RRNP FGVD ICCR KGSR SPLQ ELYN PIQL ELSN TAVL HQMR RDQV TDTC RANS ATSR KRRV LTPN DLKH LVVD EDHE LIYC YVPK VACT NWKR LMMV LTGR GKYS DPME IPAN EAHV SANL KTLN QYSI PEIN HRLK SYMK FLFV REPF ERLV SAYR NKFT QKYN ISFH KRYG TKII KRQR KNAT QEAL RKGD DVKF EEFV AYLI DPHT QREE PFNE HWQT VYSL CHPC HIHY DLVG KYET LEED SNYV LQLA GVGS YLKF PTYA KSTR TTDE MTTE FFQN ISSE HQTQ LYEV YKLD FLMF NYSV PSYL KLE |
| Gene ID: | 50515 |
| Uniprot: | Q9NPF2 |
| Cellular Location: | Golgi apparatus membrane, Single-pass type II membrane protein |
| Calculated MW: | 41kDa |
| Observed MW: | 42kDa |
| Synonyms: | CHST11, C4ST, C4ST-1, C4ST1, HSA269537 |
| Background: | The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving this gene and IgH, t(12;14)(q23;q32), has been reported in a patient with B-cell chronic lymphocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| NCBI Summary: | The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving this gene and IgH, t(12;14)(q23;q32), has been reported in a patient with B-cell chronic lymphocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] |
| UniProt Code: | Q9NPF2 |
| NCBI GenInfo Identifier: | 61212137 |
| NCBI Gene ID: | 50515 |
| NCBI Accession: | Q9NPF2.1 |
| UniProt Related Accession: | Q9NPF2 |
| Molecular Weight: | |
| NCBI Full Name: | Carbohydrate sulfotransferase 11 |
| NCBI Synonym Full Names: | carbohydrate sulfotransferase 11 |
| NCBI Official Symbol: | CHST11 |
| NCBI Official Synonym Symbols: | C4ST; C4ST1; OCBMD; C4ST-1; HSA269537 |
| NCBI Protein Information: | carbohydrate sulfotransferase 11 |
| UniProt Protein Name: | Carbohydrate sulfotransferase 11 |
| UniProt Synonym Protein Names: | Chondroitin 4-O-sulfotransferase 1; Chondroitin 4-sulfotransferase 1; C4S-1; C4ST-1; C4ST1 |
| UniProt Gene Name: | CHST11 |
| UniProt Entry Name: | CHSTB_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CHST11 antibody (CAB13734) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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