Metabolism Antibodies 2

Anti-CHORDC1 Antibody (CAB17135)

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SKU:
CAB17135
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism

Description

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Antibody Name:Anti-CHORDC1 Antibody
Antibody SKU:CAB17135
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 60-160 of human CHORDC1 (NP_036256.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 60-160 of human CHORDC1 (NP_036256.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:TKGR HNSE KPPE PVKP EVKT TEKK ELCE LKPK FQEH IIQA PKPV EAIK RPSP DEPM TNLE LKIS ASLK QALD KLKL SSGN EENK KEED NDEI KIGT SCKN G
Gene ID:26973
Uniprot:Q9UHD1
Cellular Location:
Calculated MW:
Observed MW:Refer to figures
Synonyms:CHORDC1, CHP1
Background:
UniProt Protein Function:CHORDC1: Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Calcium-binding

Chromosomal Location of Human Ortholog: 11q14.3

Molecular Function:protein binding; zinc ion binding; Hsp90 protein binding

UniProt Code:Q9UHD1
NCBI GenInfo Identifier:221316570
NCBI Gene ID:26973
NCBI Accession:NP_001137545.1
UniProt Secondary Accession:Q9UHD1,Q6IN49, Q8WVL9, Q9H3D6, B2R6P8,
UniProt Related Accession:Q9UHD1
Molecular Weight:37490
NCBI Full Name:cysteine and histidine-rich domain-containing protein 1 isoform b
NCBI Synonym Full Names:cysteine and histidine-rich domain (CHORD) containing 1
NCBI Official Symbol:CHORDC1  
NCBI Official Synonym Symbols:CHP1  
NCBI Protein Information:cysteine and histidine-rich domain-containing protein 1
UniProt Protein Name:Cysteine and histidine-rich domain-containing protein 1
UniProt Synonym Protein Names:CHORD domain-containing protein 1; CHORD-containing protein 1; CHP-1; Protein morgana
Protein Family:Cysteine and histidine-rich domain-containing protein
UniProt Gene Name:CHORDC1  
UniProt Entry Name:CHRD1_HUMAN
Anti-CHORDC1 Antibody (CAB17135)Western blot analysis of extracts of mouse thymus, using CHORDC1 antibody (CAB17135) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.
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