Immunology Antibodies 2

Anti-CHID1 Antibody (CAB16142)

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SKU:
CAB16142
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology

Description

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Antibody Name:Anti-CHID1 Antibody
Antibody SKU:CAB16142
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-393 of human CHID1 (NP_076436.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse pancreas
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-393 of human CHID1 (NP_076436.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MRTL FNLL WLAL ACSP VHTT LSKS DAKK AASK TLLE KSQF SDKP VQDR GLVV TDLK AESV VLEH RSYC SAKA RDRH FAGD VLGY VTPW NSHG YDVT KVFG SKFT QISP VWLQ LKRR GREM FEVT GLHD VDQG WMRA VRKH AKGL HIVP RLLF EDWT YDDF RNVL DSED EIEE LSKT VVQV AKNQ HFDG FVVE VWNQ LLSQ KRVG LIHM LTHL AEAL HQAR LLAL LVIP PAIT PGTD QLGM FTHK EFEQ LAPV LDGF SLMT YDYS TAHQ PGPN APLS WVRA CVQV LDPK SKWR SKIL LGLN FYGM DYAT SKDA REPV VGAR YIQT LKDH RPRM VWDS QASE HFFE YKKS RSGR HVVF YPTL KSLQ VRLE LARE LGVG VSIW ELGQ GLDY FYDL L
Gene ID:66005
Uniprot:Q9BWS9
Cellular Location:Lysosome, Secreted
Calculated MW:41kDa/44kDa/47kDa
Observed MW:55kDa
Synonyms:CHID1, GL008, SI-CLP, SICLP
Background:
UniProt Protein Function:CHID1: Saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin neutralization. Ligand-binding specificity relates to the length of the oligosaccharides, with preference for chitotetraose (in vitro). Belongs to the glycosyl hydrolase 18 family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Secreted, signal peptide; Hydrolase; Secreted

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: extracellular space; membrane; lysosome; late endosome; trans-Golgi network; nucleus

Molecular Function:protein binding; chitin binding; chitinase activity

Biological Process: carbohydrate metabolic process; innate immune response; chitin catabolic process

UniProt Code:Q9BWS9
NCBI GenInfo Identifier:218083182
NCBI Gene ID:66005
NCBI Accession:NP_001136146.1
UniProt Secondary Accession:Q9BWS9,Q8NBM9, Q96CZ3, Q96S93, Q96SK0, Q9BY52, B3KWB0
UniProt Related Accession:Q9BWS9
Molecular Weight:41,678 Da
NCBI Full Name:chitinase domain-containing protein 1 isoform a
NCBI Synonym Full Names:chitinase domain containing 1
NCBI Official Symbol:CHID1  
NCBI Official Synonym Symbols:GL008; SICLP; SI-CLP  
NCBI Protein Information:chitinase domain-containing protein 1; stabilin-1 interacting chitinase-like protein; stabilin-1-interacting chitinase-like protein
UniProt Protein Name:Chitinase domain-containing protein 1
UniProt Synonym Protein Names:Stabilin-1-interacting chitinase-like protein; SI-CLP
Protein Family:Chitinase domain-containing protein
UniProt Gene Name:CHID1  
UniProt Entry Name:CHID1_HUMAN
Anti-CHID1 Antibody (CAB16142)Western blot analysis of extracts of mouse pancreas, using CHID1 antibody (CAB16142) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
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